Mouse Monoclonal Antibody to DDX20

Mouse IgG1

MW: 92.2kDa
Enterez GeneID: 11218
General Information: DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which has an ATPase activity and is a component of the survival of motor neurons (SMN) complex. This protein interacts directly with SMN, the spinal muscular atrophy gene product, and may play a catalytic role in the function of the SMN complex on RNPs. ;
Immunogen: Purified recombinant fragment of human DDX20 (AA: 725-824) expressed in E. Coli.
Size and Concentration: 100ug/1mg/ml
Supplied As: Lyophilized Powder from 100ul of Purified antibody in PBS with 0.05% sodium azide
Reconstitution and Storage: Reconstituted with 100ul sterile DI H2O, at stored at 4C or -20C for short or long term storage.
Applications: ELISA: 1 to 10000; WB: 1 to 500 - 1 to 2000; IHC: ; ICC: 1 to 200 - 1 to 1000; FCM: 1 to 200 - 1 to 400
References: 1.J Clin Invest. 2014 Sep; 124(9):3807-24. ; 2.J Biol Chem. 1999 Jul 2; 274(27):19136-44.;