Mouse Monoclonal Antibody to B7H3

Mouse IgG1

MW: 57.2kDa
Enterez GeneID: 80381
General Information: The protein encoded by this gene belongs to the immunoglobulin superfamily, and thought to participate in the regulation of T-cell-mediated immune response. Studies show that while the transcript of this gene is ubiquitously expressed in normal tissues and solid tumors, the protein is preferentially expressed only in tumor tissues. Additionally, it was observed that the 3' UTR of this transcript contains a target site for miR29 microRNA, and there is an inverse correlation between the expression of this protein and miR29 levels, suggesting regulation of expression of this gene product by miR29. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Immunogen: Purified recombinant fragment of human B7H3 (AA: extra 29-466) expressed in HEK293 cells.
Size and Concentration: 100ug/1mg/ml
Supplied As: Lyophilized Powder from 100ul of Purified antibody in PBS with 0.05% sodium azide
Reconstitution and Storage: Reconstituted with 100ul sterile DI H2O, at stored at 4C or -20C for short or long term storage.
Applications: ELISA: 1 to 10000; WB: 1 to 500 - 1 to 2000; ICC: N to A; FCM: N to A; IHC: N to A
References: 1.Blood. 2013 Aug 8; 122(6):922-31. 2.Breast Cancer Res Treat. 2010 Feb; 120(1):195-202.