« Back
Home /
Polatuzumab vedotin-piiq (ADC)

Polatuzumab vedotin-piiq (ADC)

Item no.	ANSY-DHE26399-5mg
Manufacturer	Antibody System
Amount	5 mg
Quantity options	5 mg
Category	Oncology Antibodies By Cell Type Hematology Lymphoma
Type	Antibody Monoclonal
Clone	Polatuzumab vedotin-piiq
Specific against	Human (Homo sapiens)
Purity	>90% as determined by SEC.
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Polivy
Available
Manufacturer - Type	Primary
Manufacturer - Applications	Research Grade Biosimilar
Manufacturer - Targets	CD79b
Storage Conditions	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Product description	Polatuzumab vedotin (Polivy) is an ADC consisting of a CD79b-directed antibody and Monomethyl auristatin E (MMAE) that can be used in combination with bendamustine and rituximab for the treatment of adult patients with at least two relapses or refractory diffuse large B-cell lymphoma. Polatuzumab vedotin binds to CD79b and is internalized by tumor cells. MMAE is cleaved from cells by lysosomal protease and promotes tumor cell apoptosis by inhibiting microtubule formation.
Purification	Purified by Ion Exchange Chromatography.
Note	For research use only. Not suitable for clinical or therapeutic use.
Clonality	Monoclonal
Concentration	1 mg/ml
Recombinant	Yes

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

Request product datasheet

Request safety datasheet

Simple Order Order Subscription

Amount: 5 mg

available

Compare

Add to wishlist

Get an offer

Request delivery time

Ask a technical question