Comparison

Research Grade Etokimab

Item no. ANSY-DHB74001-100ug
Manufacturer AntibodySystem
CASRN 2022981-44-6
Amount 100 ug
Quantity options 100 ug 1 mg
Category
Type Biosimilars
Format Liquid
Clone Etokimab
Specific against Human (Homo sapiens)
Isotype IgG1 Kappa
Purity >95% as determined by SDS-PAGE.
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Alias ANB020,CAS: 2022981-44-6,IL33
Shipping Condition Cool pack
Available
Manufacturer - Type
Primary
Manufacturer - Applications
Research Grade Biosimilar
Manufacturer - Category
Biosimilar
Manufacturer - Targets
NF-HEV, IL-1F11, C9orf26, IL-33, Interleukin-1 family member 11, IL33, Nuclear factor from high endothelial venules, NFHEV, Interleukin-33, IL1F11
Manufacturer - Host
Humanized
Shipping Temperature
Blue-ice bags
Storage Conditions
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Product description
ANB020, now called etokimab, is currently in phase 2a testing in eczema, which is also known as atopic dermatitis. Scientists from the Medical Research Council Human Immunology Unit at the University of Oxford released data from 12 patients showing that 83% who were treated with etokimab reported a reduction in disease severity after 29 days. Etokimab, an anti-IL-33 biologic, has previously demonstrated a good safety profile and favorable pharmacodynamic properties in many clinical studies. Etokimab is designed to block interleukin-33 (IL-33), an immune-signaling molecule. In peanut allergy, the body overreacts to peanuts as IL-33 activates an antibody called immunoglobin E. These antibodies cause allergic response such as mouth itchiness, hives, breathing difficulties and potentially fatal anaphylactic shock.
Manufacturer - Formula
0.01M PBS, pH 7.4.
Storage buffer
0.01M PBS, pH 7.4.
Purification
Protein A/G purified from cell culture supernatant.
Note
For research use only. Not suitable for clinical or therapeutic use.
Clonality
Monoclonal
Concentration
1 mg/ml
Recombinant
Yes
Expression System
Mammalian Cells

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100 ug
Available: In stock
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