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Research Grade Sotigalimab

Research Grade Sotigalimab

Item no.	ANSY-DHD68911-1mg
Manufacturer	Antibody System
CASRN	2305607-45-6
Amount	1 mg
Quantity options	100 ug 1 mg
Category	Oncology Neuroscience Neural Lineage Markers Aging & Neurological Disorders Antibodies In Vivo Antibodies By Cell Type Hematology Lymphoma Neurodegeneration Markers
Clone	Sotigalimab
Specific against	Human (Homo sapiens)
Purity	>95% as determined by SDS-PAGE.
Alias	APX005M,APX-005,APX-005-M,APX-005M,CAS: 2305607-45-6
Available
Manufacturer - Type	Primary
Manufacturer - Applications	Research Grade Biosimilar
Manufacturer - Targets	Tumor necrosis factor receptor superfamily member 5, B-cell surface antigen CD40, Bp50, CD40L receptor, TNFRSF5, CDw40, CD40
Manufacturer - Host	Humanized
Storage Conditions	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Product description	The FDA has granted an orphan drug designation to sotigalimab (APX005M) as a potential therapeutic option for patients with soft tissue sarcoma, according to announcement from Apexigen Inc., the drug developer. A novel, humanized monoclonal antibody, sotigalimab was designed stimulate antitumor immune response and to target CD40, which is a key co-stimulatory receptor that serves to activate innate and adaptive immune systems. When sotigalimab binds to CD40 on antigen-presenting cells, it induces a multifaceted immune response that brings several components of the immune system together to attack the cancer.
Storage buffer	0.01M PBS, pH 7.4.
Purification	Protein A/G purified from cell culture supernatant.
Note	For research use only. Not suitable for clinical or therapeutic use.
Clonality	Monoclonal
Concentration	1 mg/ml
Recombinant	Yes
Expression System	Mammalian Cells

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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