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Anti-Digoxin Antibody (26G10)

Anti-Digoxin Antibody (26G10)

Item no.	ANSY-RGK23001-50ug
Manufacturer	AntibodySystem
Amount	50 ug
Quantity options	100 ug 50 ug
Category	Antibodies Immunoprecipitation Western Blot ELISA Immunoassay Primary Antibodies Immunostaining CLIA Dot Blot
Type	Antibody Monoclonal
Applications	WB, IP, ELISA, CLIA, IA, Dot
Clone	26G10
Specific against	other
Host	Mouse
Purity	>95% as determined by SDS-PAGE.
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Available
Manufacturer - Type	Primary
Manufacturer - Applications	CLIA, DB, ELISA, IP, RIA, WB
Manufacturer - Targets	Digoxin, DGX, CAS: 20830-75-5, digoxinum, 12β-hydroxydigitoxin, ChEBI: 4551, 26-10#, 26G10
Storage Conditions	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Product description	The antibody is specific for digoxin, a cardiac glycoside derived from the foxglove plant. Digoxin is administered for the therapeutic treatment of heart conditions such as atrial fibrillation, atrial flutter and heart failure, an acts by inhibiting the Na+/K+ ATPase. However, the drug has a very narrow therapeutic index and can cause toxic side effects. The Fab fragment prepared from 26-10 that neutralises the activity of digoxin and can be used as an antidote in case of overdose of digitalis. Anti-digoxin monoclonal antibodies can also be used to measure serum levels of the drug as a guide to therapy, and are useful in the investigation of the kinetics of interaction between antibody and antigen.
Storage buffer	100 mM Pro-Ac, 20 mM Arg, pH 5.0
Purification	Protein A/G purified from cell culture supernatant.
Note	For research use only.
Clonality	Monoclonal
Concentration	3.15 mg/ml

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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