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DR1 Antibody - N-terminal region

DR1 Antibody - N-terminal region

Item no.	ARP38085_T100-25UL
Manufacturer	AVIVA Systems Biology
Amount	25 ul
Category	Neuroscience Molecular Targets for Neuroscience Aging & Neurological Disorders Neural Signaling Protein Aggregation, Clearance & Misfolding Antibodies Western Blot Primary Antibodies
Type	Antibody Polyclonal
Format	Liquid
Applications	WB
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus), Rabbit (Oryctolagus cuniculus), Guinea Pig, Dog (Canine, Canis lupus familiaris), Horse (Equine), Zebrafish (Danio rerio), Cow (Bos taurus)
Host	Rabbit
Sequence	MASSSGNDDDLTIPRAAINKMIKETLPNVRVANDARELVVNCCTEFIHLI
Citations	Deng, W., MalecovÃƒÂ¡, B., OelgeschlÃƒÂ¤ger, T. & Roberts, S. G. E. TFIIB recognition elements control the TFIIA-NC2 axis in transcriptional regulation. Mol. Cell. Biol. 29, 1389-400 (2009). 19114554 Gilfillan,S., et al., (2005) J. Biol. Chem. 280 (7), 6222-6230
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	NC2,NC2B,NCB2,NC2-BETA
Shipping Condition	Cool pack
Available
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Polyclonal Antibodies/Transcription Regulation, Root Catalog/Research Areas/Chromatin & Nuclear Signaling, Root Catalog/Research Areas/DNA\/RNA\/Protein Interactions, Root Catalog/Research Areas/Chromatin Immunoprecipitation, Root Catalog/Research Areas/Acetylation, Root Catalog/Research Areas/Transcription Factors, Root Catalog/Products/Polyclonal Antibodies/Trial Size Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies, Root Catalog/Products/Aviva Rabbit Polyclonal
Shipping Temperature	Wet Ice
Molecular Weight	19kDa
Species Tested	Human
Gene symbol	DR1
Gene Fullname	Down-regulator of transcription 1, TBP-binding (negative cofactor 2)
Protein size	176
Product format	Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution and storage	For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Partner proteins	POLE3; TBP; UBC; BTF3L4; LRSAM1; GOPC; NPLOC4; IPO11; DBNL; ARIH1; TTLL12; ARPC1B; UBE3A; METTL1; HSF1; XPO1; YEATS2; DRAP1; CREB1; CCDC101; TADA2B; SUPT20H; MBIP; WDR5; TADA3; KAT2B; MAP3K7; TADA2A; KAT2A; DR1; ELAVL1; NFYC; NFIL3; TTF2; IRF1;
Description of target	DR1 is a TBP- (TATA box-binding protein) associated phosphoprotein that represses both basal and activated levels of transcription. DR1 is phosphorylated in vivo and this phosphorylation affects its interaction with TBP. DR1 contains a histone fold motif
Nucleotide accession_num	NM_001938
Protein accession_num	NP_001929
Protein name	Protein Dr1
Clonality	Polyclonal
Purification	Protein A purified
Immunogen	The immunogen is a synthetic peptide directed towards the N terminal region of human DR1
Homology	Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%
Concentration	1.0 mg/ml

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 25 ul

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Delivery expected until 10/30/2025

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