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CFLAR Antibody - C-terminal region

CFLAR Antibody - C-terminal region

Item no.	AVARP02011_P050-25UL
Manufacturer	AVIVA Systems Biology
Amount	25 ul
Category	Oncology Neuroscience Neural Lineage Markers Metabolism Diabetes Glucose Homeostasis Molecular Targets for Neuroscience Targets for Rodent Neurosciences Aging & Neurological Disorders Neural Signaling Protein Aggregation, Clearance & Misfolding Antibodies By Cell Type Carcinoma Hematology Leukemia Lymphoma Cell Biology Cell Status Apoptosis Western Blot Primary Antibodies Neurodegeneration Markers
Type	Antibody Polyclonal
Format	Liquid
Applications	WB
Specific against	Human (Homo sapiens)
Host	Rabbit
Sequence	LRQERKRPLLDLHIELNGYMYDWNSRVSAKEKYYVWLQHTLRKKLILSYT
Citations	Geserick,P., (2008) Oncogene 27 (22), 3211-3220
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	CASH,FLIP,MRIT,CLARP,FLAME,cFLIP,Casper,FLAME1,c-FLIP,FLAME-1,I-FLICE,c-FLIPL,c-FLIPR,c-FLIPS,CASP8AP1
Shipping Condition	Cool pack
Available
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Polyclonal Antibodies/Lymphocyte Signaling, Root Catalog/Research Areas/Apoptosis, Root Catalog/Products/Polyclonal Antibodies/Trial Size Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies, Root Catalog/Products/Aviva Rabbit Polyclonal
Shipping Temperature	Wet Ice
Molecular Weight	55kDa
Species Tested	Human
Gene symbol	CFLAR
Gene Fullname	CASP8 and FADD-like apoptosis regulator
Protein size	480
Product format	Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution and storage	For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Partner proteins	FADD; TRAF1; GSN; SPATS1; TNFSF10; RIPK1; RAF1; SMAD3; CASP8; HSP90AA1; STUB1; TNFRSF10A; TNFRSF10B; UBC; FASLG; ITCH; DAXX; CBLB; ATG3; XRCC6; Mib1; TP53; DEDD2; DEDD; RIPK2; IKBKB; MAP2K7; TRAF2; CASP10; CASP7; CASP6; MAP2K4; PSEN2; CASP2; CASP3; BCL2L1
Description of target	CFLAR belongs to the peptidase C14A family. It is a apoptosis regulator protein which may function as a crucial link between cell survival and cell death pathways in mammalian cells. The protein acts as an inhibitor of TNFRSF6 mediated apoptosis. Full length and shorter isoforms have been shown either to induce apoptosis or to reduce TNFRSF-triggered apoptosis. CFLAR lacks enzymatic (caspase) activity.
Nucleotide accession_num	NM_003879
Protein accession_num	NP_003870
Protein name	CASP8 and FADD-like apoptosis regulator
Clonality	Polyclonal
Purification	Affinity Purified
Immunogen	The immunogen is a synthetic peptide directed towards the C-terminal region of human CFLAR
Homology	Human: 100%
Concentration	0.5 mg/ml
Sample Type Confirmation	CFLAR is strongly supported by BioGPS gene expression data to be expressed in 721_B

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 25 ul

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Delivery expected until 2/12/2026

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