Anti-Dopamine beta Hydroxylase/DBH Antibody Picoband®

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

51735 MW

Western blot, 0.1-0.25μg/ml, Human, Mouse, Rat
ELISA, 0.1-0.5μg/ml

dopamine beta-hydroxylase

Dopamine beta-hydroxylase  (DBH), also known as  dopamine beta-monooxygenase, is an  enzyme  (EC1.14.17.1) that in humans is encoded by the DBH  gene. Dopamine beta-hydroxylase  catalyzes  the  chemical reaction. It is mapped to 9q34.2. The protein encoded by this gene is an oxidoreductase belonging to the copper type II, ascorbate-dependent monooxygenase family. The encoded protein, expressed in neuroscretory vesicles and chromaffin granules of the adrenal medulla, catalyzes the conversion of dopamine to norepinephrine, which functions as both a hormone and as the main neurotransmitter of the sympathetic nervous system. The enzyme encoded by this gene exists exists in both soluble and membrane-bound forms, depending on the absence or presence, respectively, of a signal peptide. Mutations in this gene cause dopamine beta-hydroxylate deficiency in human patients, characterized by deficits in autonomic and cardiovascular function, including hypotension and ptosis. Polymorphisms in this gene may play a role in a variety of psychiatric disorders.

Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.01mg NaN3.

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

DNA/RNA, Epigenetics and Nuclear Signaling, Translation

Conversion of dopamine to noradrenaline.

Boster Bio Anti-Dopamine beta Hydroxylase/DBH Antibody Picoband® catalog # A01110. Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

No cross-reactivity with other proteins.