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Anti-Angiotensinogen/AGT Antibody Picoband®

Anti-Angiotensinogen/AGT Antibody Picoband®

Item no.	BOS-A02103-3-carrier-free
Manufacturer	Boster
Amount	100 ug
Quantity options	100 ug/vial 10 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug
Category	Neuroscience Neural Signaling Antibodies Flow Cytometry Immunohistochemistry Western Blot ELISA Cardiovascular Research Heart Failure Myocardial Infarction Hypertension Primary Antibodies Immunostaining
Type	Antibody
Format	Lyophilized
Applications	WB, FC, IHC, ELISA
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Citations	1. Abonia, J. P., Abel, K. J., Eddy, R. L., Elliott, R. W., Chapman, V. M., Shows, T. B., Gross, K. W. Linkage of Agt and Actsk-1 to distal mouse chromosome 8 loci: a new conserved linkage. Mammalian Genome 4: 25-32, 1993. 2. Arakawa, K., Minohara, A., Yamada, J., Nakamura, M. Enzymatic degradation and electrophoresis of human angiotensin I. Biochim. Biophys. Acta 168: 106-112, 1968. 3. Basso N, Terragno NA (December 2001). History about the discovery of the renin-angiotensin system. Hypertension 38 (6): 1246–9.
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Angiotensinogen,Serpin A8,Angiotensin-1,Angiotensin 1-10,Angiotensin I,Ang I,Angiotensin-2,Angiotensin 1-8,Angiotensin II,Ang II,Angiotensin-3,Angiotensin 2-8,Angiotensin III,Ang III,Des-Asp[1]-angiotensin II,Angiotensin-4,Angiotensin 3-8,Angiotensin IV,Ang IV,Angiotensin 1-9,Angiotensin 1-7,Angiotensin 1-5,Angiotensin 1-4,Agt,Serpina8
Available
Manufacturer - Category	Primary Antibodies
Manufacturer - Conjugate / Tag	carrier-free
Storage Conditions	At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
Observed Molecular weight	55 kDa
Calculated Molecular weight	51990 MW
Clonality	Polyclonal
Application Details	Western blot, 0.25-0.5 μg/ml, Human Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/ml, Human Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human ELISA, 0.1-0.5 μg/ml
Gene Name	AGT
Gene Full Name	Angiotensinogen
Background	AGT(ANGIOTENSINOGEN), also called SERPINA8, is an α-2-globulin that is produced constitutively and released into the circulation mainly by the liver. ATG is a member of the serpin family, although it is not known to inhibit other enzymes, unlike most serpins. Angiotensinogen is also known as renin substrate. The AGT gene is mapped on 1q42.2. And the human angiotensinogen gene contains 5 exons. The expression of AGT and enzymes required for its conversion to angiotensin II in human adipose tissue. Mutations in this AGT gene are associated with susceptibility to essential hypertension, and can cause renal tubular dysgenesis, a severe disorder of renal tubular development. Defects in this gene have also been associated with non-familial structural atrial fibrillation, and inflammatory bowel disease.
Immunogen	E.coli-derived human Angiotensinogen/AGT recombinant protein (Position: D34-R458).
Contents	Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
Purification	Immunogen affinity purified.
Reconstitution	Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.
Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.
Manufacturer - Research Category	Cardiovascular, G Protein Signaling, Signal Transduction, Signaling Pathway
Protein Name	Angiotensinogen
Protein Function	Essential component of the renin-angiotensin system (RAS), a potent regulator of blood pressure, body fluid and electrolyte homeostasis.
Subcellular Localization	Secreted.
Description	Boster Bio Anti-Angiotensinogen/AGT Antibody Picoband® catalog # A02103-3. Tested in ELISA, Flow Cytometry, IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Tissue Specificity	Expressed by the liver and secreted in plasma.
Manufacturer - Alias	Angiotensinogen, Serpin A8, Angiotensin-1, Angiotensin 1-10, Angiotensin I, Ang I, Angiotensin-2, Angiotensin 1-8, Angiotensin II, Ang II, Angiotensin-3, Angiotensin 2-8, Angiotensin III, Ang III, Des-Asp[1]-angiotensin II, Angiotensin-4, Angiotensin 3-8, Angiotensin IV, Ang IV, Angiotensin 1-9, Angiotensin 1-7, Angiotensin 1-5, Angiotensin 1-4, Agt, Serpina8
Manufacturer - Cross Reactivity	No cross-reactivity with other proteins

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

BOS-A02103-3-carrier-free-datasheet.pdf

BOS-A02103-3-carrier-free-safety-datasheet.pdf