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Anti-TL1A/TNFSF15 Antibody Picoband®

Anti-TL1A/TNFSF15 Antibody Picoband®

Item no.	BOS-A02402-1-FITC
Manufacturer	Boster
Amount	100 ug
Quantity options	100 ug/vial 10 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug
Category	Oncology Antibodies Cell Biology Cell Status Apoptosis Immunohistochemistry Western Blot ELISA Primary Antibodies By Organ Colorectal Cancer Immunostaining
Type	Antibody Primary
Format	Lyophilized
Applications	WB, IHC, ELISA
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	FITC
Citations	1. Entrez Gene: TNFSF15 tumor necrosis factor (ligand) superfamily, member 15. 2. Picornell Y, Mei L, Taylor K, Yang H, Targan SR, Rotter JI (Nov 2007). TNFSF15 is an ethnic-specific IBD gene. Inflammatory Bowel Diseases. 13 (11): 1333–8.
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Tumor necrosis factor ligand superfamily member 15,TNF ligand-related molecule 1,Vascular endothelial cell growth inhibitor,Tumor necrosis factor ligand superfamily member 15,membrane form,Tumor necrosis factor ligand superfamily member 15,secreted form,TNFSF15,TL1,VEGI
Available
Manufacturer - Applications	ELISA (Cap), IHC, WB
Manufacturer - Category	Primary Antibodies
Storage Conditions	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
Observed Molecular weight	28 kDa
Clonality	Polyclonal
Application Details	Western blot, 0.1-0.5μg/ml Immunohistochemistry (Paraffin-embedded Section), 0.5-1μg/ml ELISA (Cap), 1-5μg/ml
Gene Name	TNFSF15
Gene Full Name	TNF superfamily member 15
Manufacturer - Specificity	No cross reactivity with other proteins.
Background	Vascular endothelial growth inhibitor (VEGI), also known as TNF-like ligand 1A (TL1A) and TNF superfamily member 15 (TNFSF15), is protein that in humans is encoded by the TNFSF15 gene. The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein is abundantly expressed in endothelial cells, but is not expressed in either B or T cells. The expression of this protein is inducible by TNF and IL-1 alpha. This cytokine is a ligand for receptor TNFRSF25 and decoy receptor TNFRSF21/DR6. It can activate NF-kappaB and MAP kinases, and acts as an autocrine factor to induce apoptosis in endothelial cells. This cytokine is also found to inhibit endothelial cell proliferation, and thus may function as an angiogenesis inhibitor. Two transcript variants encoding different isoforms have been found for this gene.
Immunogen	E. coli-derived human TL1A recombinant protein (Position: L72-T244).
Contents	Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na₂HPO₄, 0.05mg NaN₃.
Purification	Immunogen affinity purified.
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.
Manufacturer - Research Category	Angiogenesis, Cardiovascular, Cytokines, Immunology, Innate Immunity, TNF Superfamily
Protein Function	Receptor for TNFRSF25 and TNFRSF6B. Mediates activation of NF-kappa-B. Inhibits vascular endothelial growth and angiogenesis (in vitro). Promotes activation of caspases and apoptosis.
Subcellular Localization	Membrane.
Description	Boster Bio Anti-TL1A/TNFSF15 Antibody Picoband® catalog # A02402-1. Tested in ELISA, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Tissue Specificity	Specifically expressed in endothelial cells. Detected in monocytes, placenta, lung, liver, kidney, skeletal muscle, pancreas, spleen, prostate, small intestine and colon.
Manufacturer - Alias	Tumor necrosis factor ligand superfamily member 15, TNF ligand-related molecule 1, Vascular endothelial cell growth inhibitor, Tumor necrosis factor ligand superfamily member 15, membrane form, Tumor necrosis factor ligand superfamily member 15, secreted form, TNFSF15, TL1, VEGI
Manufacturer - Cross Reactivity	No cross-reactivity with other proteins.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

BOS-A02402-1-FITC-datasheet.pdf

BOS-A02402-1-FITC-safety-datasheet.pdf