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Anti-Calbindin/CALB1 Antibody Picoband®

Anti-Calbindin/CALB1 Antibody Picoband®

Item no.	BOS-A03047-Dylight488
Manufacturer	Boster
Amount	100 ug
Quantity options	100 ug/vial 10 ug 100 ug/vial 100 ug/vial 100 ug/vial 100 ug 100 ug 100 ug 100 ug/vial 100 ug/vial 100 ug/vial 100 ug/vial 100 ug/vial
Category	Neuroscience Neural Lineage Markers Molecular Targets for Neuroscience Antibodies Flow Cytometry Immunohistochemistry Western Blot ELISA Immunofluorescence Primary Antibodies Immunostaining Calcium Binding Protein Markers Neurodegeneration Markers Microglia Markers
Type	Antibody Polyclonal
Format	Lyophilized
Applications	WB, FC, IF, IHC, ELISA
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	DyLight 488
Citations	1. Parmentier M.; The human calbindins: cDNA and gene cloning.;Adv. Exp. Med. Biol. 255:233-240(1989). 2. Strauss K.I., Kuznicki J., Winsky L., Kawagoe J.I., Hammer M., Jacobowitz D.M.;The mouse calretinin gene promoter region: structural and functional components.;Brain Res. Mol. Brain Res. 49:175-187(1997). 3. Gabrielides C., McCormack A.L., Hunt D.F., Christakos S.;Brain calbindin-D28k and an Mr 29,000 calcium binding protein in cerebellum are different but related proteins: evidence obtained from sequence analysis by tandem mass spectrometry.;Biochemistry 30:656-662(1991).
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Calbindin,Calbindin D28,D-28K,Vitamin D-dependent calcium-binding protein,avian-type,CALB1,CAB27
Available
Manufacturer - Category	Primary Antibodies
Storage Conditions	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
Molecular Weight	28 kDa
Calculated Molecular weight	30, 025 MW
Clonality	Polyclonal
Application Details	Western blot, 0.1-0.5μg/ml, Mouse, Rat Immunohistochemistry (Paraffin-embedded Section), 0.5-1μg/ml, Human, Mouse, Rat Immunofluorescence, 5 μg/ml, Rat Flow Cytometry (Fixed), 1-3μg/1x10⁶ cells, Human ELISA, 0.1-0.5μg/ml
Gene Name	CALB1
Gene Full Name	calbindin 1, 28kDa
Background	Calbindin is a calcium-binding protein belonging to the troponin C superfamily. And it mapped to 8q21.3. Calretinin is expressed in central and peripheral nervous system and in many normal and pathological tissues. The rat and human calretinin exhibit 98% sequence homology and 91% homology to many other species. Two calcium binding proteins, calbindin and calretinin, have been reported to be expressed in abundance in Purkinje cells and other cell types in the cerebellum.
Immunogen	E. coli-derived human Calbindin recombinant protein (Position: A2-N261).
Contents	Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na₂HPO₄, 0.05mg NaN₃.
Purification	Immunogen affinity purified.
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.
Manufacturer - Research Category	Calcium Binding Proteins, Calcium Signaling, Cell Type Marker, Neuron Marker, Neuroscience, Neurotransmission
Protein Function	Buffers cytosolic calcium. May stimulate a membrane Ca (2+)-ATPase and a 3', 5'-cyclic nucleotide phosphodiesterase.
Subcellular Localization	Hemidesmosome, Membrane, Single-pass type II membrane protein, Basement membrane.
Description	Boster Bio Anti-Calbindin/CALB1 Antibody Picoband® catalog # A03047. Tested in ELISA, Flow Cytometry, IF, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Tissue Specificity	Detected in skin. In the cornea, it is detected in the epithelial basement membrane, the epithelial cells, and at a lower level in stromal cells. Stratified squamous epithelia. Found in hemidesmosomes. Expressed in cornea, oral mucosa, esophagus, intestine, kidney collecting ducts, ureter, bladder, urethra and thymus but is absent in lung, blood vessels, skeletal muscle and nerves.
Manufacturer - Cross Reactivity	No cross-reactivity with other proteins.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

BOS-A03047-Dylight488-datasheet.pdf

BOS-A03047-Dylight488-safety-datasheet.pdf