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Anti-HDAC10 Antibody Picoband®

Anti-HDAC10 Antibody Picoband®

Item no.	BOS-A05215-2-PE
Manufacturer	Boster
Amount	100 ug
Quantity options	100 ug/vial 10 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug
Category	Oncology Neuroscience Aging & Neurological Disorders Neural Epigenetics Antibodies By Cell Type Carcinoma Hematology Lymphoma Melanoma Sarcoma Western Blot ELISA Primary Antibodies Immunostaining
Type	Antibody Polyclonal
Format	Lyophilized
Applications	WB, ELISA
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	PE
Citations	1. Entrez Gene: HDAC10 histone deacetylase 10. 2. Kao HY, Lee CH, Komarov A, Han CC, Evans RM (Jan 2002). Isolation and characterization of mammalian HDAC10, a novel histone deacetylase. J Biol Chem. 277 (1): 187–93. 3. Guardiola AR, Yao TP (Jan 2002). Molecular cloning and characterization of a novel histone deacetylase HDAC10. J Biol Chem. 277 (5): 3350–6.
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Histone deacetylase 10,HD10,HDAC10
Available
Manufacturer - Category	Primary Antibodies
Storage Conditions	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
Observed Molecular weight	71 kDa
Calculated Molecular weight	39411 MW
Clonality	Polyclonal
Application Details	Western blot, 0.1-0.5μg/ml ELISA, 0.1-0.5μg/ml
Gene Name	HDAC10
Gene Full Name	histone deacetylase 10
Manufacturer - Specificity	No cross reactivity with other proteins.
Background	Histone deacetylase 10 is an enzyme that in humans is encoded by the HDAC10 gene. The protein encoded by this gene belongs to the histone deacetylase family, members of which deacetylate lysine residues on the N-terminal part of the core histones. Histone deacetylation modulates chromatin structure, and plays an important role in transcriptional regulation, cell cycle progression, and developmental events. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Immunogen	E. coli-derived human HDAC10 recombinant protein (Position: T3-Q290).
Contents	Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na₂HPO₄, 0.05mg NaN₃.
Purification	Immunogen affinity purified.
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.
Manufacturer - Research Category	Acetylation, Chromatin Modifying Enzymes, Class I, Epigenetics and Nuclear Signaling, Signaling Pathways, Stem Cells
Protein Name	Long-chain-fatty-acid--CoA ligase 5
Protein Function	Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.
Subcellular Localization	Cytoplasm. Nucleus. Excluded from the nucleoli.
Description	Boster Bio Anti-HDAC10 Antibody Picoband® catalog # A05215-2. Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Tissue Specificity	Ubiquitous. High expression in liver, spleen, pancreas and kidney.
Manufacturer - Cross Reactivity	No cross-reactivity with other proteins.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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BOS-A05215-2-PE-datasheet.pdf

BOS-A05215-2-PE-safety-datasheet.pdf