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Anti-Nefh Antibody Picoband®

Anti-Nefh Antibody Picoband®

Item no.	BOS-A05307-PE
Manufacturer	Boster
Amount	100 ug
Quantity options	100 ug/vial 10 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug
Category	Neuroscience Neural Lineage Markers Molecular Targets for Neuroscience Antibodies Flow Cytometry Immunohistochemistry Western Blot ELISA Primary Antibodies Immunostaining Neurodegeneration Markers Glial Cell Markers
Type	Primary Antibody
Format	Lyophilized
Applications	WB, FC, IHC, ELISA
Specific against	Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	PE
Citations	1. Lees, J. F., Shneidman, P. S., Skuntz, S. F., Carden, M. J., Lazzarini, R. A. The structure and organization of the human heavy neurofilament subunit (NF-H) and the gene encoding it. EMBO J. 7: 1947-1955, 1988. 2. Mattei, M.-G., Dautigny, A., Pham-Dinh, D., Passage, E., Mattei, J.-F., Jolles, P. The gene encoding the large human neurofilament subunit (NF-H) maps to the q121-q131 region on human chromosome 22. Hum. Genet. 80: 293-295, 1988. 3. Rao, M. V., Houseweart, M. K., Williamson, T. L., Crawford, T. O., Folmer, J., Cleveland, D. W. Neurofilament-dependent radial growth of motor axons and axonal organization of neurofilaments does not require the neurofilament heavy subunit (NF-H) or its phosphorylation. J. Cell Biol. 143: 171-181, 1998.
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Loricrin,LOR,LRN
Available
Manufacturer - Category	Primary Antibodies
Storage Conditions	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
Observed Molecular weight	117-220 kDa
Calculated Molecular weight	39411 MW
Clonality	Polyclonal
Application Details	Western blot, 0.1-0.25μg/ml, Mouse, Rat Immunohistochemistry (Paraffin-embedded Section), 2-5μg/ml, Mouse, Rat Flow Cytometry (Fixed), 1-3μg/1x10⁶ cells, Mouse ELISA, 0.1-0.5μg/ml
Gene Name	Nefh
Gene Full Name	loricrin
Background	Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the heavy neurofilament protein. This protein is commonly used as a biomarker of neuronal damage and susceptibility to amyotrophic lateral sclerosis (ALS) has been associated with mutations in this gene.
Immunogen	E.coli-derived mouse Nefh recombinant protein (Position: Y109-E466).
Contents	Each vial contains 4mg Trehalose, 0.9mg NaCl and 0.2mg Na2HPO4.
Purification	Immunogen affinity purified.
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.
Manufacturer - Research Category	Cell Biology, Cytokines, Epigenetics and Nuclear Signaling, Immunology, Innate Immunity, Interferons, Proteasome / Ubiquitin, Proteolysis/Ubiquitin, Ubiquitin & Ubiquitin Like Modifiers, Ubiquitin E3 Enzymes
Protein Name	Zinc finger protein Helios
Protein Function	Major keratinocyte cell envelope protein.
Subcellular Localization	Nucleoplasm. Cytoplasm.
Description	Boster Bio Anti-Nefh Antibody Picoband® catalog # A05307. Tested in ELISA, Flow Cytometry, IHC, WB applications. This antibody reacts with Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Tissue Specificity	Expressed in testis and to a lesser degree in brain, ovary and placenta. Found in most tissues at low levels.
Manufacturer - Cross Reactivity	No cross-reactivity with other proteins.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

BOS-A05307-PE-datasheet.pdf

BOS-A05307-PE-safety-datasheet.pdf