Comparison

Anti-Tubulin beta Antibody Picoband® European Partner

Item no. BOS-A05397-1-APC
Manufacturer Boster
Amount 100 ug/vial
Quantity options 100 ug/vial 10 ug 100 ug/vial 100 ug/vial 100 ug/vial 100 ug 100 ug 100 ug 100 ug/vial 100 ug/vial 100 ug/vial 100 ug/vial
Category
Type Primary Antibody
Format Lyophilized
Applications WB, FC, IF, IHC, ICC, ELISA
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host Rabbit
Isotype IgG
Conjugate/Tag APC
Citations 1. Davis, B., Toivio-Kinnucan, M., Schuller, S., Boudreaux, M. K. Mutation in beta-1-tubulin correlates with macrothrombocytopenia in Cavalier King Charles Spaniels. J. Vet. Intern. Med. 22: 540-545, 2008.
2. Freson, K., De Vos, R., Wittevrongel, C., Thys, C., Defoor, J., Vanhees, L., Vermylen, J., Peerlinck, K., Van Geet, C. The TUBB1 Q43P functional polymorphism reduces the risk of cardiovascular disease in men by modulating platelet function and structure. Blood 106: 2356-2362, 2005.
3. Kunishima, S., Kobayashi, R., Itoh, T. J., Hamaguchi, M., Saito, H. Mutation of the beta-1-tubulin gene associated with congenital macrothrombocytopenia affecting microtubule assembly. Blood 113: 458-461, 2009.
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias RNA binding protein fox-1 homolog 2,Fox-1 homolog B,Hexaribonucleotide-binding protein 2,RNA-binding motif protein 9,RNA-binding protein 9,Repressor of tamoxifen transcriptional activity,RBFOX2,FOX2,HRNBP2,RBM9,RTA
Available
Manufacturer - Category
Primary Antibodies
Storage Conditions
Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
Observed Molecular weight
55 kDa
Calculated Molecular weight
39411 MW
Clonality
Polyclonal
Application Details
Western blot, 0.25-0.5μg/ml, Human, Mouse, Rat
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/ml, Human
Immunocytochemistry/Immunofluorescence, 5μg/ml, Human
Flow Cytometry (Fixed), 1-3μg/1x106 cells, Human
ELISA, 0.1-0.5μg/ml
Gene Name
TUBB1
Gene Full Name
RNA binding fox-1 homolog 2
Background
TUBB1 is a gene that codes for the protein Tubulin beta-1 chain in humans. This gene encodes a member of the beta tubulin protein family. Beta tubulins are one of two core protein families (alpha and beta tubulins) that heterodimerize and assemble to form microtubules. This protein is specifically expressed in platelets and megakaryocytes and may be involved in proplatelet production and platelet release. A mutations in this gene is associated with autosomal dominant macrothrombocytopenia. Two pseudogenes of this gene are found on chromosome Y.
Immunogen
E.coli-derived human Tubulin beta recombinant protein (Position: A18-D435).
Contents
Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
Purification
Immunogen affinity purified.
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Concentration
Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.
Manufacturer - Research Category
Cardiogenesis, Cardiovascular, Domain Families, Epigenetics and Nuclear Signaling, Hlh/Leucine Zipper, Neurology Process, Neuroscience, Receptors, Transcription, Transcription Factors, Transcription Factors/Regulators
Protein Name
Zinc finger protein Helios
Protein Function
RNA-binding protein that regulates alternative splicing events by binding to 5'-UGCAUGU-3' elements. Prevents binding of U2AF2 to the 3'-splice site. Regulates alternative splicing of tissue-specific exons and of differentially spliced exons during erythropoiesis (By similarity). RNA-binding protein that seems to act as a coregulatory factor of ER-alpha.
Subcellular Localization
Nucleus. Cytoplasm.
Description
Boster Bio Anti-Tubulin beta Antibody Picoband® catalog # A05397-1. Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Tissue Specificity
Expressed in fetal brain. Highly expressed in brain and placenta. Lower levels in heart, liver, thymus, kidney and lung. Located to endothelial cells and neuronal cells of the suprachiasmatic nucleus (SCN). Also detected in endothelial cells of the heart, lung and kidney. In the brain, specifically expressed in the thalamus, hippocampus and amygdala.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100 ug/vial
Available: In stock
available

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