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Anti-RND1 Antibody Picoband®

Anti-RND1 Antibody Picoband®

Item no.	BOS-A06347-HRP
Manufacturer	Boster
Amount	100 ug
Quantity options	100 ug/vial 10 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug
Category	Antibodies Cell Biology Cytoskeleton Western Blot Primary Antibodies small GTPases Rho Subfamily
Type	Antibody Polyclonal
Format	Lyophilized
Applications	WB
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	HRP
Citations	1. Ridley AJ (Oct 2006). Rho GTPases and actin dynamics in membrane protrusions and vesicle trafficking. Trends in Cell Biology. 16 (10): 522–9. 2. Vayssière B, Zalcman G, Mahé Y, Mirey G, Ligensa T, Weidner KM, Chardin P, Camonis J (Feb 2000). Interaction of the Grb7 adapter protein with Rnd1, a new member of the Rho family. FEBS Letters. 467 (1): 91–6.
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Rho-related GTP-binding protein Rho6,Rho family GTPase 1,Rnd1,RND1,RHO6
Available
Manufacturer - Category	Primary Antibodies
Storage Conditions	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
Observed Molecular weight	26 kDa
Calculated Molecular weight	26056 MW
Clonality	Polyclonal
Application Details	Western blot, 0.1-0.5μg/ml, Mouse, Human
Gene Name	RND1
Gene Full Name	Rho-related GTP-binding protein Rho6
Manufacturer - Specificity	No cross reactivity with other proteins.
Background	Rnd1 is a small (~21 kDa) signaling G protein (to be specific, a GTPase), and is a member of the Rndsubgroup of the Rho family of GTPases. Members of this family regulate the organization of the actin cytoskeleton in response to extracellular growth factors. A similar protein in rat interacts with a microtubule regulator to control axon extension. The RND1 gene is mapped to chromosome 12q12-q13.
Immunogen	E. coli-derived human RND1 recombinant protein (Position: K105-C229). Human RND1 shares 95.2% amino acid (aa) sequence identity with mouse RND1.
Contents	Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na₂HPO₄, 0.05mg NaN₃.
Purification	Immunogen affinity purified.
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.
Manufacturer - Research Category	Actin Assembly, Actin, etc., Cytoskeleton, Cytoskeleton/ECM, G Protein Signaling, Microfilaments, Ras Family, Signal Transduction, Signaling Pathway, Small G Proteins
Protein Name	AP-2 complex subunit mu
Protein Function	Lacks intrinsic GTPase activity. Has a low affinity for GDP, and constitutively binds GTP. Controls rearrangements of the actin cytoskeleton. Induces the Rac-dependent neuritic process formation in part by disruption of the cortical actin filaments. Causes the formation of many neuritic processes from the cell body with disruption of the cortical actin filaments.
Subcellular Localization	Cell membrane; Lipid-anchor; Cytoplasmic side. Cytoplasm, cytoskeleton.
Description	Boster Bio Anti-RND1 Antibody Picoband® catalog # A06347. Tested in WB applications. This antibody reacts with Human, Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Tissue Specificity	Mostly expressed in brain and liver.
Manufacturer - Cross Reactivity	No cross-reactivity with other proteins.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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BOS-A06347-HRP-datasheet.pdf

BOS-A06347-HRP-safety-datasheet.pdf