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Anti-GPR50 Antibody Picoband®

Anti-GPR50 Antibody Picoband®

Item no.	BOS-A07827-2-Dylight594
Manufacturer	Boster
Amount	100 ug
Quantity options	100 ug/vial 10 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug
Category	Neuroscience Molecular Targets for Neuroscience Antibodies Western Blot ELISA Primary Antibodies Immunostaining
Type	Antibody
Format	Lyophilized
Applications	WB, ELISA
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	DyLight 594
Citations	1. Gubitz, A. K., Reppert, S. M. Assignment of the melatonin-related receptor to human chromosome X (GPR50) and mouse chromosome X (Gpr50). Genomics 55: 248-251, 1999. 2. Levoye, A., Dam, J., Ayoub, M. A., Guillaume, J.-L., Couturier, C., Delagrange, P., Jockers, R. The orphan GPR50 receptor specifically inhibits MT1 melatonin receptor function through heterodimerization. EMBO J. 25: 3012-3023, 2006. 3. Reppert, S. M., Weaver, D. R., Ebisawa, T., Mahle, C. D., Kolakowski, L. F., Jr. Cloning of a melatonin-related receptor from human pituitary. FEBS Lett. 386: 219-224, 1996.
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Protein SOX-15,Protein SOX-12,Protein SOX-20,SOX15,SOX12,SOX20,SOX26,SOX27
Available
Manufacturer - Category	Primary Antibodies
Storage Conditions	At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
Observed Molecular weight	67 kDa
Calculated Molecular weight	49229 MW
Clonality	Polyclonal
Application Details	Western blot, 0.25-0.5 μg/ml, Mouse ELISA, 0.1-0.5 μg/ml
Gene Name	GPR50
Gene Full Name	SRY-box 15
Background	G protein-coupled receptor 50 is a protein which in humans is encoded by the GPR50 gene. This gene product belongs to the G-protein coupled receptor 1 family. Even though this protein shares similarity with the melatonin receptors, it does not bind melatonin, however, it inhibits melatonin receptor 1A function through heterodimerization. Polymorphic variants of this gene have been associated with bipolar affective disorder in women.
Immunogen	E.coli-derived human GPR50 recombinant protein (Position: K214-S471).
Contents	Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
Purification	Immunogen affinity purified.
Reconstitution	Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.
Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.
Manufacturer - Research Category	Golgi Proteins, Protein Trafficking, Signal Transduction, Vesicle Transport
Protein Name	Chromaffin granule amine transporter
Protein Function	Binds to the 5'-AACAAT-3' sequence.
Subcellular Localization	Nucleus.
Description	Boster Bio Anti-GPR50 Antibody Picoband® catalog # A07827-2. Tested in ELISA, WB applications. This antibody reacts with Human, Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Tissue Specificity	Widely expressed in fetal and adult tissues examined, highest level found in fetal spinal cord and adult brain and testis.
Manufacturer - Cross Reactivity	No cross-reactivity with other proteins.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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BOS-A07827-2-Dylight594-datasheet.pdf

BOS-A07827-2-Dylight594-safety-datasheet.pdf