Comparison

Anti-beta Defensin 1/DEFB1 Antibody Picoband® European Partner

Item no. BOS-PA1450-APC
Manufacturer Boster
Amount 100 ug
Quantity options 100 ug/vial 10 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug
Category
Type Antibody Polyclonal
Format Lyophilized
Applications WB, IHC
Specific against Human (Homo sapiens)
Host Rabbit
Isotype IgG
Conjugate/Tag APC
Sensitivity <10 pg/ml
Sequence Belongs to the beta-defensin family.
Citations 1. Jia, H. P., Starner, T., Ackermann, M., Kirby, P., Tack, B. F., McCray, P. B., Jr.Abundant human beta-defensin-1 expression in milk and mammary gland epithelium.J.
2. Liu, L., Zhao, C., Heng, H. H. Q., Ganz, T.The human beta-defensin-1 and alpha-defensins are encoded by adjacent genes: two peptide families with differing disulfide topology share a common ancestry.
3. Valore, E. V., Park, C. H., Quayle, A. J., Wiles, K. R., McCray, P. B., Jr., Ganz, T.Human beta-defensin-1: an antimicrobial peptide of urogenital tissues.J. Clin.
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Beta-defensin 1,BD-1,hBD-1,Defensin,beta 1,DEFB1,BD1,HBD1
Available
Manufacturer - Category
Primary Antibodies
Storage Conditions
Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
Observed Molecular weight
7 kDa
Calculated Molecular weight
7420 MW
Clonality
Polyclonal
Application Details
Immunohistochemistry (Paraffin-embedded Section), 0.5-1μg/ml, Human
Western blot, 0.1-0.5μg/ml, Human
Gene Name
DEFB1
Gene Full Name
Beta-defensin 1
Manufacturer - Specificity
No cross reactivity with other proteins.
Background
DEFB1, Beta-defensin 1, is a protein that in humans is encoded by the DEFB1 gene. DEFB1 belongs to the defensin family. Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. The DEFB1 gene spans more than 7 kb and includes a large 6, 962-bp intron. By 2-color fluorescence in situ hybridization on both metaphase chromosomes and released chromatin fiber, the DEFB1gene is mapped to 8p23.2-p23.1, within 100 to 150 kb of the gene for human neutrophil defensin-alpha-1. DEFB1may augment neonatal host defenses through antimicrobial effects or prime the adaptive immune system at mucosal surfaces.
Immunogen
A synthetic peptide corresponding to a sequence at the C-terminus of human beta Defensin 1.
Contents
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Purification
Immunogen affinity purified.
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Concentration
Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.
Manufacturer - Research Category
Cell Biology
Protein Name
Beta-defensin 1(BD-1/hBD-1)
Protein Function
Has bactericidal activity.
Subcellular Localization
Secreted.
Description
Boster Bio Anti-beta Defensin 1/DEFB1 Antibody catalog # PA1450. Tested in IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Tissue Specificity
Plasma.
Sequence Similarities
Belongs to the beta-defensin family.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100 ug
Available: In stock
available

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