Comparison

Anti-IL2 Receptor gamma/IL2RG Antibody Picoband® European Partner

Item no. BOS-PA1616-Cy3
Manufacturer Boster
Amount 100 ug
Quantity options 100 ug/vial 10 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug
Category
Type Antibody Polyclonal
Format Lyophilized
Applications WB
Specific against Human (Homo sapiens)
Host Rabbit
Isotype IgG
Conjugate/Tag Cy3
Sensitivity <10 pg/ml
Sequence Belongs to the type I cytokine receptor family. Type 5 subfamily.
Citations 1. Asao, H., Okuyama, C., Kumaki, S., Ishii, N., Tsuchiya, S., Foster, D., Sugamura, K. Cutting edge: the common gamma-chain is an indispensable subunit of the IL-21 receptor complex. J. Immun. 167: 1-5, 2001.
2. Brandt, K., Singh, P. B., Bulfone-Paus, S., Ruckert, R. Interleukin-21: a new modulator of immunity, infection, and cancer. Cytokine Growth Factor Rev. 18: 223-232, 2007.
3. PDB 2B5IWang X, Rickert M, Garcia KC (November 2005). Structure of the quaternary complex of interleukin-2 with its alpha, beta, and gammac receptors. Science 310 (5751): 1159–63. doi:10.1126/science.1117893. PMID 16293754.
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Cytokine receptor common subunit gamma,Interleukin-2 receptor subunit gamma,IL-2 receptor subunit gamma,IL-2R subunit gamma,IL-2RG,gammaC,p64,CD132,IL2RG
Available
Manufacturer - Category
Primary Antibodies
Storage Conditions
Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
Observed Molecular weight
75 kDa
Calculated Molecular weight
42287 MW
Clonality
Polyclonal
Application Details
Western blot, 0.1-0.5μg/ml, Human
Gene Name
IL2RG
Gene Full Name
Cytokine receptor common subunit gamma
Manufacturer - Specificity
No cross reactivity with other proteins.
Background
IL2RG (INTERLEUKIN 2 RECEPTOR, GAMMA), also known as Common gamma chain or CD132, is a cytokine receptor sub-unit that is common to the receptor complexes for at least six different interleukin receptors:IL-2, IL-4, IL-7, IL-9, IL-15 and interleukin-21 receptor. IL2RG is a member of the type I cytokine receptor family expressed on most lymphocyte (white blood cell) populations, and its gene is found on the X-chromosome of mammals. By fluorescence in situ hybridization and PCR amplification of somatic cell hybrid DNAs, The IL2RG gene is mapped to Xq13.1. The IL2RG gene contains 8 exons and spans approximately 4.2 kb. And the gamma chain is an indispensable component of the functional IL2 receptor. Lymphocytes expressing the common gamma chain can form functional receptors for these cytokine proteins, which transmit signals from one cell to another and programs of cellular differentiation. The sharing of the gamma subunit by several receptors explains why humans and mice that lack IL2 entirely show milder symptoms than those with IL2RG deficiency.
Immunogen
A synthetic peptide corresponding to a sequence in the middle region of human IL2 Receptor gamma.
Contents
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Purification
Immunogen affinity purified.
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Concentration
Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.
Manufacturer - Research Category
Cancer, Cell Type Markers, Cytokines, Immunology, Innate Immunity, Interleukins, Tumor Immunology
Protein Name
Cytokine receptor common subunit gamma
Protein Function
Common subunit for the receptors for a variety of interleukins.
Subcellular Localization
Membrane; Single-pass type I membrane protein.
Description
Boster Bio Anti-IL2 Receptor gamma/IL2RG Antibody catalog # PA1616. Tested in WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Sequence Similarities
Belongs to the type I cytokine receptor family. Type 5 subfamily.
Manufacturer - Cross Reactivity
No cross-reactivity with other proteins

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100 ug
Available: In stock
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