Comparison

Stat5(Phospho-Tyr694) Rabbit Polyclonal Antibody

Item no. BT-AP12838-100ul
Manufacturer Bioassay Technology Laboratory
Amount 100 ul
Category
Type Antibody Polyclonal
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host Rabbit
Isotype IgG
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Stat5 ;Tyr694; Signal transducer and activator of transcription 5B
Available
Background
The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors| STAT family members are phosphorylated by the receptor associated kinases| and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein mediates the signal transduction triggered by various cell ligands| such as IL2| IL4| CSF1| and different growth hormones. It has been shown to be involved in diverse biological processes| such as TCR signaling| apoptosis| adult mammary gland development| and sexual dimorphism of liver gene expression. This gene was found to fuse to retinoic acid receptor-alpha (RARA) gene in a small subset of acute promyelocytic leukemias (APLL). The dysregulation of the signaling pathways mediated by this protein may be the cause of the APLL.
Clonality
Polyclonal
Concentration
1 mg/ml
Immunogen
Synthesized phosho peptide around human Stat5 (Tyr694)
Storage Stability
-20°C for 1 year

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100 ul
Available: In stock
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