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FAS Polyclonal Antibody

FAS Polyclonal Antibody

Item no.	E-AB-40063-25uL
Manufacturer	Elabscience
Amount	25 uL
Quantity options	100 uL 120 uL 20 uL 200 uL 25 uL 60 uL
Category	Oncology Neuroscience Neuroinflammation Metabolism Diabetes Cholesterol & Lipid Metabolism Antibodies By Cell Type Carcinoma Cell Biology Obesity Cell Culture Cytokines Cell Status Necrosis Apoptosis Immunohistochemistry Western Blot Cardiovascular Research Ischemia & Reperfusion Injury Enzymes Fatty Acid Synthesis Primary Antibodies
Type	Antibody Polyclonal
Applications	WB, IHC
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
Citations	https://www.frontiersin.org/articles/10.3389/fonc.2021.735183/full https://www.mdpi.com/1422-0067/20/3/757 https://onlinelibrary.wiley.com/doi/abs/10.1002/tox.22942 https://www.sciencedirect.com/science/article/pii/S0006291X19316687
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	ALPS 1A, ALPS1A, APO 1, Apo 1 antigen, APO 1 cell surface antigen, Apo-1 antigen, APO1, Apo1 antigen, APO1 cell surface antigen, Apoptosis antigen 1, Apoptosis mediating surface antigen FAS, Apoptosis-mediating surface antigen FAS, APT 1, APT1, CD 95, CD 95 antigen, CD95, CD95 antigen, Delta Fas, Delta Fas/APO 1/CD95, Delta Fas/APO1/CD95, Fas (TNF receptor superfamily, member 6), FAS 1, FAS 827dupA, Fas AMA, Fas, FAS Antigen, Fas cell surface death receptor, FAS1, FASLG receptor, FASTM, sFAS, Surface antigen APO1, TNF receptor superfamily, member 6, TNFRSF 6, TNFRSF6, TNR6, Tumor necrosis factor receptor superfamily member 6
Shipping Condition	Cool pack
Hazard information	Comply with cargo safety certificate
Available
Manufacturer - Category	Primary Antibodies
Manufacturer - Targets	FAS
Shipping Temperature	The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions	Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight	37kDa
Observed Molecular Weight	45kDa
Manufacturer - Research Areas	Cancer, Cell Biology, Immunology
Background	Fas (CD95/APO-1) is a transmembrane glycoprotein belonging to the tumor necrosis factor (TNF) receptor superfamily. It can mediates apoptosis by ligation with an agonistic anti-Fas antibody or Fas ligand. Stimulation of Fas results in the aggregation of its intracellular death domains, leading to the formation of the death-inducing signaling complex (DISC). FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. The molecular mass of native Fas is 38 kDa, the high molecular weight form (40-55 kDa) of Fas is due to glycosylation.
Concentration	1 mg/mL
Buffer	PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4
Purification Method	Antigen Affinity Purification
Recommended Dilution	WB 1:500-1:1000; IHC 1:50-1:100
Abbreviation	FAS
Clonality	Polyclonal
Immunogen	Recombinant Human Tumor necrosis factor receptor superfamily member 6 protein
Category ID III	Polyclonal Antibodies

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.