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Purified Anti-Mouse CD161/NK1.1 Antibody[PK136]

Purified Anti-Mouse CD161/NK1.1 Antibody[PK136]

Item no.	E-AB-F0987A-5mg
Manufacturer	Elabscience
Amount	5 mg
Quantity options	100 ug 100 mg 1 mg 25 ug 25 mg 50 ug 5 mg
Category	Oncology Antibodies By Cell Type Carcinoma Hematology Myeloma Cell Biology Cell Status Apoptosis Flow Cytometry Immunohistochemistry Immunofluorescence Primary Antibodies
Type	Antibody Monoclonal
Applications	FC
Clone	PK136
Specific against	Mouse (Murine, Mus musculus)
Host	Mouse
Isotype	IgG2a Kappa
Conjugate/Tag	Unconjugated
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Killer cell lectin-like receptor subfamily B member 1C, Klrb1c, CD161 antigen-like family member C, Ly-55c, CD161/NK1.1, NKR-P1.9, NKR-P1C, NKR-P1 40, CD161c,
Shipping Condition	Cool pack
Hazard information	Comply with cargo safety certificate
Available
Manufacturer - Applications	FCM
Manufacturer - Category	Flow Cytometry Antibodies
Manufacturer - Isotype	Mouse IgG2a, κ
Manufacturer - Targets	CD161/NK1.1
Shipping Temperature	Ice bag
Storage Conditions	Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.
Background	NK-1.1 surface antigen, also known as CD161b/CD161c and Ly-55, is encoded by the NKR-P1B/NKR-P1C gene. It is expressed on NK cells and NK-T cells in some mouse strains, including C57BL/6, FVB/N, and NZB, but not AKR, BALB/c, CBA/J, C3H, DBA/1, DBA/2, NOD, SJL, and 129. Expression of NKR-P1C antigen has been correlated with lysis of tumor cells in vitro and rejection of bone marrow allografts in vivo. NK-1.1 has also been shown to play a role in NK cell activation, IFN-γ production, and cytotoxic granule release. NK-1.1 and DX5 are commonly used as mouse NK cell markers.
Concentration	≥1 mg/mL
Buffer	Phosphate buffered solution, pH 7.2, containing 0.05% proclin 300.
Abbreviation	CD161/NK1.1
Clonality	Monoclonal
Usage	Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 10^6 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.