PIK3R1 Polyclonal Antibody

WB, IHC, ELISA. Other applications have not been tested.

Store at 4C or -20C (with 50% glycerol); Minimize freeze-thaw cycles; Non-hazardous.

The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. Multiple alternatively spliced transcript variants that encode different protein isoforms have been found for this gene.

alin-fixed and paraffin-embedded human breastcarcinoma reacted with EGFR Antibody.