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Anti-Ankyrin-G (Staining) Antibody

Anti-Ankyrin-G (Staining) Antibody

Item no.	75-146
Manufacturer	Antibodies Incorporated
Amount	100 uL
Quantity options	100 uL 20 uL
Category	Neuroscience Neural Signaling Antibodies Immunohistochemistry Immunocytochemistry Primary Antibodies
Type	Antibody Monoclonal
Format	Liquid
Applications	WB, IP, IHC, ICC
Clone	N106/36
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus), Hamster, Cat (Feline, Felis catus), Primate
Host	Mouse
Isotype	IgG2a
Conjugate/Tag	Unconjugated
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Ankyrin-3 (ANK-3) (Ankyrin-G)
Shipping Condition	Cool pack
Available
Manufacturer - Type	Primary Antibody
Manufacturer - Targets	Ankyrin-G (Staining)
Country of Origin	United States
Shipping Temperature	Shipped on ice packs
Storage Conditions	Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
Molecular Weight	<200 kDa
Manufacturer - Research Area	Cell Markers, Neuronal Markers, Axonal Markers, Scaffold Proteins
Expiration	24 months from date of receipt
Immunogen	Fusion protein ~1000 amino acids of Ankyrin-G (accession number E9PE32) produced recombinantly in E. Coli
Immunogen Species	Human
Description	Our Anti-Ankyrin-G (Staining) mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N106/36. It detects feline, hamster, human, mouse, non-human primate, and rat Ankyrin-G (Staining), and is purified by Protein A chromatography. It is great for use in IHC, ICC, IP, WB.
Target Description	Ankyrin-G (ankyrin 3) is a member of the Ankyrin family which consists of Ankyrin R (1), Ankyrin B (2) and Ankyrin G (3) all of which are expressed in the nervous system. Ankyrins are structural proteins that aid in the attachment of integral membrane proteins with the spectrin-actin cytoskeleton, and thus targets voltage-gated sodium channels, potassium channels, cell adhesion molecules and others at the nodes of Ranvier and axonal initial segments (AIS). Variants in Ankyrin G have been linked to bipolar disorder.
Clonality	Monoclonal
Manufacturer - Specificity	Does not cross-react with Ankyrin-B
Concentration	1 mg/mL
Form	Purified by Protein A chromatography
Buffer	10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.72
Production Notes	Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.
Quality Control	Each new lot of antibody is quality control tested by IHC on either rat or mouse brain and confirmed to give the expected staining pattern.
Quality Control: Application	IHC
Dilution Range: WB	1:1000
Dilution Range: IHC	1:500
Dilution Range: ICC	1:500
Usage Statement	These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.
Manufacturer - Statement	We produce our Ankyrin-G (Staining) mouse monoclonal primary antibody from hybridoma clone N106/36. It is great in IHC, ICC, IP, WB and is purified by Protein A chromatography.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 uL

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Delivery expected until 8/28/2025

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