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Anti-ASIC1 Antibody

Anti-ASIC1 Antibody

Item no.	75-277
Manufacturer	Antibodies Incorporated
Amount	100 uL
Category	Neuroscience Neural Signaling Antibodies Immunohistochemistry Immunocytochemistry Primary Antibodies Immunoblot
Type	Antibody Monoclonal
Format	Liquid
Applications	WB, IP, IHC, ICC
Clone	N271/44
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Mouse
Isotype	IgG1
Conjugate/Tag	Unconjugated
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Acid-sensing ion channel 1 (ASIC1) (Acid-sensing ion channel) (Amiloride-sensitive cation channel 2, neuronal) (Brain sodium channel 2) (BNaC2)
Shipping Condition	Cool pack
Available
Manufacturer - Type	Primary Antibody
Manufacturer - Targets	ASIC1
Country of Origin	United States
Shipping Temperature	Shipped on ice packs
Storage Conditions	Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
Molecular Weight	60 kDa
Manufacturer - Research Area	Ion Channels and Modulators, Other Ion Channels
Expiration	24 months from date of receipt
Immunogen	Fusion protein amino acids 460-526 (cytoplasmic C-terminus) of mouse ASIC1 (accession number Q6NXK8) produced recombinantly in E. Coli
Immunogen Species	Mouse
Description	Our Anti-ASIC1 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N271/44. It is KO validated, detects mouse and rat ASIC1, and is purified by Protein A chromatography. It is great for use in IHC, ICC, WB.
Target Description	Acid sensing ion channel 1, Neuronal amiloride-sensitive cation channel 2 or ASIC1 is encoded by the gene ASIC1 and is a member of the Acid sensing ion channel (ASIC) family. ASIC1 acts as an acid sensing proton gated sodium channel and is thought to play a role in learning, pain transduction, memory development, and fear conditioning. ASIC1 is widely expressed in the central and peripheral nervous system. Diseases associated with ASIC1 include spatial learning and memory capability problems and Frozen Shoulder.
Clonality	Monoclonal
Manufacturer - Specificity	Does not cross-react with ASIC2
Concentration	1 mg/mL
Form	Purified by Protein A chromatography
Buffer	10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.125
Production Notes	Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.
Quality Control	Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.
Quality Control: Application	WB Brain
Dilution Range: WB	1:1000
Dilution Range: IHC	1:1000
Dilution Range: IP	1.5 µL
Usage Statement	These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.
Manufacturer - Statement	We produce our ASIC1 mouse monoclonal primary antibody from hybridoma clone N271/44. It is great in IHC, ICC, WB and is purified by Protein A chromatography.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 uL

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Delivery expected until 9/11/2025

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