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Anti-Nav1.4 Sodium Channel Antibody

Anti-Nav1.4 Sodium Channel Antibody

Item no.	75-424
Manufacturer	Antibodies Incorporated
Amount	100 uL
Category	Antibodies Cardiovascular Research Ischemia & Reperfusion Injury Primary Antibodies
Type	Antibody Monoclonal
Format	Liquid
Applications	WB, IHC, ICC
Clone	N255/38
Specific against	Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Mouse
Isotype	IgG2a
Conjugate/Tag	Unconjugated
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Sodium channel protein type 4 subunit alpha (Mu-1) (SkM1) (Sodium channel protein skeletal muscle subunit alpha) (Sodium channel protein type IV subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.4)
Shipping Condition	Cool pack
Available
Manufacturer - Type	Primary Antibody
Manufacturer - Targets	Nav1.4 sodium channel
Country of Origin	United States
Shipping Temperature	Shipped on ice packs
Storage Conditions	Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
Molecular Weight	>200 kDa
Manufacturer - Research Area	Ion Channels and Modulators, Na+ Channels
Expiration	24 months from date of receipt
Immunogen	Fusion protein amino acids 269-386 (Repeat I external pore between S5 and S6) of rat Nav1.4 (accession number P15390) produced recombinantly in E. Coli
Immunogen Species	Rat
Description	Our Anti-Nav1.4 sodium channel mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N255/38. It detects rat Nav1.4 sodium channel, and is purified by Protein A chromatography. It is great for use in IHC, ICC, WB.
Target Description	Sodium channel subunit beta-1or Navbeta1 Na+ channel is encoded by SCN1B. Voltage gated sodium channels are made up of an alpha (pore forming) subunit and 1 or 2 beta subunits. SCN1B has two splice variants. Navß1 is a transmembrane protein and acts as a regulatory subunit in excitable membranes and modulates the kinetics of channel inactivation. It is found expressed in brain, spinal cord, heart and skeletal muscle. Diseases associated with SCN1B include several types of epilepsy.
Clonality	Monoclonal
Manufacturer - Specificity	No cross-reactivity reported
Concentration	1 mg/mL
Form	Purified by Protein A chromatography
Buffer	10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.125
Production Notes	Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.
Quality Control	Each new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern.
Quality Control: Application	ICC
Usage Statement	These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.
Manufacturer - Statement	We produce our Nav1.4 sodium channel mouse monoclonal primary antibody from hybridoma clone N255/38. It is great in IHC, ICC, WB and is purified by Protein A chromatography.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 uL

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Delivery expected until 9/25/2025

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