Comparison

LMCD1 Antibody (C-term) [AMM06311G]

Item no. LBI-AMM06311G-1
Manufacturer Leading Biology
Amount 400 ul
Quantity options 100 ul 400 ul 200 ul 50 ul
Category
Type Antibody
Applications WB
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host Rabbit
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias LIM and cysteine-rich domains protein 1, Dyxin, LMCD1
Available
Manufacturer - Type
Polyclonal Antibodies
Manufacturer - Category
Abs-G
Storage Conditions
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Molecular Weight
40833
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.This product is a high quality LMCD1 Antibody (C-term) [AMM06311G].
Manufacturer - Specificity
This LMCD1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 316-350 amino acids from the C-terminal region of human LMCD1.
Cellular localization
Cytoplasm. Nucleus. Note=May shuttle between the cytoplasm and the nucleus.
Gene Name
LMCD1
Function
Transcriptional cofactor that restricts GATA6 function by inhibiting DNA-binding, resulting in repression of GATA6 transcriptional activation of downstream target genes. Represses GATA6- mediated trans activation of lung- and cardiac tissue-specific promoters. Inhibits DNA-binding by GATA4 and GATA1 to the cTNC promoter (By similarity). Plays a critical role in the development of cardiac hypertrophy via activation of calcineurin/nuclear factor of activated T-cells signaling pathway.
Summary
Tissue Location: Expressed in the heart (at protein level). Expressed in many tissues with highest abundance in skeletal muscle
Dilution
WB-1:1000
Clonality
Polyclonal

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 400 ul
Available: In stock
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