Comparison

Phospho-ANTXR1 (Y425) Antibody [APG02967G]

Item no. LBI-APG02967G
Manufacturer Leading Biology
Amount 100 ul
Quantity options 100 ul
Category
Type Antibody
Format Liquid
Applications Dot
Specific against Human (Homo sapiens)
Host Rabbit
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Anthrax toxin receptor 1, Tumor endothelial marker 8, ANTXR1, ATR, TEM8
Available
Manufacturer - Type
Polyclonal Antibodies
Manufacturer - Category
Abs-G
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Molecular Weight
62789
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.This product is a high quality Phospho-ANTXR1 (Y425) Antibody [APG02967G].
Manufacturer - Specificity
This ANTXR1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y425 of human ANTXR1.
Cellular localization
Cell membrane; Single-pass type I membrane protein. Cell projection, lamellipodium membrane; Single-pass type I membrane protein. Cell projection, filopodium membrane; Single- pass type I membrane protein. Note=At the membrane of lamellipodia and at the tip of actin-enriched filopodia (PubMed:16762926). Colocalizes with actin at the base of lamellipodia (PubMed:16762926).
Gene Name
ANTXR1 {ECO:0000303|PubMed:22912819, ECO:0000312|HGNC:HGNC:21014}
Function
Plays a role in cell attachment and migration. Interacts with extracellular matrix proteins and with the actin cytoskeleton. Mediates adhesion of cells to type 1 collagen and gelatin, reorganization of the actin cytoskeleton and promotes cell spreading. Plays a role in the angiogenic response of cultured umbilical vein endothelial cells.
Summary
Tissue Location: Detected in umbilical vein endothelial cells (at protein level). Highly expressed in tumor endothelial cells
Manufacturer - Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by two-step phosphospecific peptide affinity purification.
Dilution
DB-1:500
Clonality
Polyclonal

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100 ul
Available: In stock
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