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Phospho-MeCP2 (S423) Antibody [APG03024G]

Phospho-MeCP2 (S423) Antibody [APG03024G]

Item no.	LBI-APG03024G
Manufacturer	Leading Biology
Amount	100 ul
Quantity options	100 ul
Category	Neuroscience Neural Lineage Markers Molecular Targets for Neuroscience Neural Epigenetics Glial Cell Marker Antibodies Immunohistochemistry Western Blot ELISA Primary Antibodies Dot Blot Glial Cell Markers
Type	Antibody
Format	Liquid
Applications	WB, IHC-P
Specific against	Human (Homo sapiens), Rat (Rattus norvegicus)
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Methyl-CpG-binding protein 2, MeCp-2 protein, MeCp2, MECP2
Available
Manufacturer - Type	Polyclonal Antibodies
Manufacturer - Applications	IHC-P-Leica, WB
Manufacturer - Category	Abs-G
Storage Conditions	Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Molecular Weight	52441
Overview	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.This product is a high quality Phospho-MeCP2 (S423) Antibody [APG03024G].
Manufacturer - Specificity	This MeCP2 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S423 of human MeCP2.
Cellular localization	Nucleus {ECO:0000250\|UniProtKB:Q9Z2D6}. Note=Colocalized with methyl-CpG in the genome. Colocalized with TBL1X to the heterochromatin foci.
Gene Name	MECP2
Function	Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Mediates transcriptional repression through interaction with histone deacetylase and the corepressor SIN3A. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)- containing DNA, with a preference for 5-methylcytosine (5mC).
Summary	Tissue Location: Present in all adult somatic tissues tested.
Manufacturer - Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Dilution	IHC-P-Leica-1:500WB-1:500
Clonality	Polyclonal

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ul

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Delivery expected until 10/16/2025

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