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Sestrin-3 Antibody (Center Y335) [APR07009G]

Sestrin-3 Antibody (Center Y335) [APR07009G]

Item no.	LBI-APR07009G
Manufacturer	Leading Biology
Amount	100 ul
Quantity options	100 ul
Category	Metabolism Diabetes Cholesterol & Lipid Metabolism Regulation of Appetite Antibodies Immunohistochemistry Western Blot ELISA Primary Antibodies
Type	Antibody
Format	Liquid
Applications	WB, IHC-P
Specific against	Human (Homo sapiens)
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Sestrin-3, SESN3, SEST3
Available
Manufacturer - Type	Polyclonal Antibodies
Manufacturer - Category	Abs-G
Storage Conditions	Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Molecular Weight	57291
Overview	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.This product is a high quality Sestrin-3 Antibody (Center Y335) [APR07009G].
Manufacturer - Specificity	This Sestrin-3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 320-347 amino acids from the Central region of human Sestrin-3.
Cellular localization	Cytoplasm.
Gene Name	SESN3
Function	May function as an intracellular leucine sensor that negatively regulates the TORC1 signaling pathway (PubMed:25263562). May also regulate the insulin-receptor signaling pathway through activation of TORC2 (By similarity). This metabolic regulator may also play a role in protection against oxidative and genotoxic stresses (By similarity). May prevent the accumulation of reactive oxygen species (ROS) through the alkylhydroperoxide reductase activity born by the N-terminal domain of the protein (By similarity).
Summary	Tissue Location: Widely expressed..
Manufacturer - Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Dilution	WB-1:2000WB-1:1000IHC-P-1:100~500
Clonality	Polyclonal

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ul

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Delivery expected until 10/16/2025

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