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ARHGAP18 Antibody (Center) [APR15009G]

ARHGAP18 Antibody (Center) [APR15009G]

Item no.	LBI-APR15009G-2
Manufacturer	Leading Biology
Amount	200 ul
Quantity options	100 ul 400 ul 200 ul 50 ul
Category	Neuroscience Neural Signaling Antibodies Cell Biology Cytoskeleton Flow Cytometry Immunohistochemistry Western Blot ELISA Primary Antibodies small GTPases Rho Subfamily
Type	Antibody
Format	Liquid
Applications	WB, FC, IHC-P
Specific against	Human (Homo sapiens)
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Rho GTPase-activating protein 18, MacGAP, Rho-type GTPase-activating protein 18, ARHGAP18 (<a href="http://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=21035" target="_blank">HGNC:21035</a>)
Available
Manufacturer - Type	Polyclonal Antibodies
Manufacturer - Category	Abs-G
Storage Conditions	Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Molecular Weight	74977
Overview	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.This product is a high quality ARHGAP18 Antibody (Center) [APR15009G].
Manufacturer - Specificity	This ARHGAP18 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 180-207 amino acids from the Central region of human ARHGAP18.
Cellular localization	Cytoplasm.
Gene Name	ARHGAP18
Function	Rho GTPase activating protein that suppresses F-actin polymerization by inhibiting Rho. Rho GTPase activating proteins act by converting Rho-type GTPases to an inactive GDP-bound state (PubMed:21865595). Plays a key role in tissue tension and 3D tissue shape by regulating cortical actomyosin network formation. Acts downstream of YAP1 and inhibits actin polymerization, which in turn reduces nuclear localization of YAP1 (PubMed:25778702). Regulates cell shape, spreading, and migration (PubMed:21865595).
Manufacturer - Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Dilution	WB-1:1000IHC-P-1:100~500FC-1:10~50
Clonality	Polyclonal

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 200 ul

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Delivery expected until 12/18/2025

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