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TLE1 Antibody - N-terminal region

TLE1 Antibody - N-terminal region

Item no.	OAAB18976
Manufacturer	AVIVA Systems Biology
Amount	400 ul
Category	Oncology Neuroscience Neural Adhesion Molecules Antibodies By Cell Type Blastoma Carcinoma Hematology Leukemia Adenocarcinoma Western Blot Immunofluorescence Primary Antibodies
Type	Antibody Polyclonal
Applications	WB, IF
Specific against	Human (Homo sapiens)
Host	Rabbit
Citations	Stifani S.,et al.Nat. Genet. 2:119-127(1992). Ota T.,et al.Nat. Genet. 36:40-45(2004). Humphray S.J.,et al.Nature 429:369-374(2004). Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases. Wang J.-C.,et al.J. Biol. Chem. 275:18418-18423(2000).
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	ESG,ESG1,GRG1
Shipping Condition	Cool pack
Available
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Manufacturer - Isotype	Rabbit Ig
Shipping Temperature	Wet Ice
Molecular Weight	83 kDa
Manufacturer - Application Additional Information	IF: 1:25 WB: 1:1000
Gene symbol	TLE1
Product format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
Reconstitution and storage	Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
Description of target	Transcriptional corepressor that binds to a number of transcription factors. Inhibits NF-kappa-B-regulated gene expression. Inhibits the transcriptional activation mediated by FOXA2, and by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES. Unusual function as coactivator for ESRRG.
Clonality	Polyclonal
Purification	This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen	This TLE1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 187-221 amino acids from the N-terminal region of human TLE1.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 400 ul

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Delivery expected until 12/25/2025

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