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PRKAB1 Antibody

PRKAB1 Antibody

Item no.	OAAB20868
Manufacturer	AVIVA Systems Biology
Amount	100 ul
Category	Oncology Metabolism Cholesterol & Lipid Metabolism Antibodies By Cell Type Hematology Lymphoma Cell Biology Obesity Cell Status Immunohistochemistry Immunoprecipitation Western Blot ELISA Immunocytochemistry Autophagy Enzymes Fatty Acid Synthesis Primary Antibodies Immunochemistry
Type	Antibody Monoclonal
Format	Liquid
Applications	WB, IP, IHC, ICC
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host	Rabbit
Citations	Carling D.,et al.Submitted (FEB-1998) to the EMBL/GenBank/DDBJ databases. Stapleton D.,et al.FEBS Lett. 409:452-456(1997). Yamagata K.,et al.Submitted (JAN-1997) to the EMBL/GenBank/DDBJ databases. Wang X.,et al.Submitted (JAN-1999) to the EMBL/GenBank/DDBJ databases. Scherer S.E.,et al.Nature 440:346-351(2006).
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	AMPK,HAMPKb
Shipping Condition	Cool pack
Available
Manufacturer - Type	Monoclonal Antibody
Manufacturer - Category	Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Molecular Weight	30 kDa
Manufacturer - Application Additional Information	WB: 1:1000 ICC: 1:100 IP: 1:500 IHC: 1:100
Gene symbol	PRKAB1
Gene Fullname	protein kinase AMP-activated non-catalytic subunit beta 1
Product format	Liquid
Reconstitution and storage	Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
Description of target	The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit may be a positive regulator of AMPK activity. The myristoylation and phosphorylation of this subunit have been shown to affect the enzyme activity and cellular localization of AMPK. This subunit may also serve as an adaptor molecule mediating the association of the AMPK complex.
Nucleotide accession_num	NM_006253.4
Protein accession_num	NP_006244.2
Clonality	Monoclonal
Homology	Human, Mouse
Formulation	Purified mouse monoclonal antibody in PBS (pH 7.4) containing with 0.02% sodium azide and 50% glycerol.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ul

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