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ZKSCAN3 Antibody - N-terminal region

ZKSCAN3 Antibody - N-terminal region

Item no.	OAAB22289
Manufacturer	AVIVA Systems Biology
Amount	200 ul
Category	Antibodies Cell Biology Cell Status Western Blot Autophagy Cardiovascular Research Heart Failure Myocardial Infarction Hypertension Primary Antibodies
Type	Antibody Polyclonal
Format	Liquid
Applications	WB
Clone	RB53917
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host	Rabbit
Citations	Kalnine N.,et al.Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases. Ota T.,et al.Nat. Genet. 36:40-45(2004). Mungall A.J.,et al.Nature 425:805-811(2003). Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases. Petroni D.,et al.DNA Seq. 9:163-169(1998).
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	ZF47,Zfp47,ZFP306,ZNF306,ZNF309,zfp-47,ZSCAN13,ZSCAN35,dJ874C20.1,dJ874C20.1.
Shipping Condition	Cool pack
Available
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Manufacturer - Isotype	Rabbit Ig
Shipping Temperature	Wet Ice
Molecular Weight	61 kDa
Manufacturer - Application Additional Information	WB: 1:2000
Gene symbol	ZKSCAN3
Gene Fullname	zinc finger with KRAB and SCAN domains 3
Product format	Liquid. PBS with 0.09% (W/V) sodium azide.
Reconstitution and storage	Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
Description of target	Transcriptional factor that binds to the consensus sequence 5'-[GT][AG][AGT]GGGG-3' and acts as a repressor of autophagy. Specifically represses expression of genes involved in autophagy and lysosome biogenesis/function such as MAP1LC3B, ULK1 or WIPI2. Associates with chromatin at the ITGB4 and VEGF promoters. Also acts as a transcription activator and promotes cancer cell progression and/or migation in various tumors and myelomas.
Nucleotide accession_num	NM_001242894.1
Protein accession_num	NP_001229823.1
Clonality	Polyclonal
Purification	Protein A column purification, followed by peptide affinity purification.
Immunogen	This ZKSCAN3 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 100-130 amino acids from human ZKSCAN3.
Concentration	0.5 mg/ml

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 200 ul

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Delivery expected until 12/25/2025

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