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Anti-STAT3 Antibody (Phospho-S 727)

Anti-STAT3 Antibody (Phospho-S 727)

Item no.	OAAI00081-100UG
Manufacturer	AVIVA Systems Biology
Amount	100 ug
Category	Oncology Neuroscience Neural Lineage Markers Neural Transcription Factors Antibodies By Cell Type Blastoma Carcinoma Glioma Hematology Leukemia Lymphoma Myeloma Melanoma Adenocarcinoma Flow Cytometry Immunohistochemistry Immunoprecipitation Western Blot ELISA Primary Antibodies
Type	Antibody Polyclonal
Format	Liquid
Applications	WB, FC, IP, IHC
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Citations	Ritsuko Matsuo et al. A new expression cloning stRategy for isolation of substRate-specific kinases by using phosphorylation site-specific Antibody. Journal of Immunological Methods. Volume 247, Issues 1-2, 1 January 2001, Pages 141-151
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	acute-phase response factor;ADMIO;ADMIO1;APRF;DNA-binding protein APRF;HIES;signal transducer and activator of transcription 3.
Shipping Condition	Cool pack
Available
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Polyclonal Antibodies/Phospho Specific, Root Catalog/Products/Primary Antibodies
Manufacturer - Isotype	Rabbit IgG
Manufacturer - Targets	Phosphorylated
Shipping Temperature	Wet Ice
Molecular Weight	94
Manufacturer - Application Additional Information	WB: 0.1-1 ug/ml \| ELISA: \| IP: 2-5 ug/ml \| IHC: 2-10 ug/ml \| FC: Not tested
Gene symbol	STAT3
Gene Fullname	signal transducer and activator of transcription 3
Product format	Liquid. This affinity purified antibody is supplied in sterile Tris-buffered saline (pH7.2) containing antibody stabilizer
Reconstitution and storage	The antibodies are stable for 24 months from date of receipt when stored at -20C to -70C. The antibodies can be stored at 2C-8C for three month without detectable loss of activity. Avoid repeated freezing-thawing cycles.
Description of target	STAT proteins (Signal transducer and activator of transcription) belong to a family of cytoplasmic transcription factors that can be phosphorylated by a lignad binding to its cell surface receptor. The phosphorylation of STAT3 induces STAT dimerization, nuclear translocation and DNA binding. Stat3 is constitutively activated in a number of Human tumors. Stat3- activated transcription seems to be regulated by serine phosphorylation at Ser727.
Clonality	Polyclonal
Purification	Affinity Purified
Immunogen	A synthetic peptide surrounding to the epitope -PMSPR-- with phosphorylation sites at Ser727 of STAT3 protein from human, mouse, rat, chicken dog and bovine origins.
Manufacturer - Specificity	STAT3
Concentration	100ug/200ul

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

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Delivery expected until 12/11/2025

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