Anti-CD40 Antibody

Item no.	OAAI00212-100UG
Manufacturer	AVIVA Systems Biology
Amount	100 ug
Category	Oncology Neuroscience Neural Lineage Markers Neuroinflammation Metabolism Diabetes Aging & Neurological Disorders Antibodies By Cell Type Hematology Lymphoma Cell Biology Obesity Cell Culture Cytokines Cell Status Necrosis Apoptosis Flow Cytometry Immunohistochemistry Immunoprecipitation Western Blot ELISA Primary Antibodies Immunostaining Neurodegeneration Markers
Type	Antibody Polyclonal
Format	Liquid
Applications	WB, FC, IP, IHC, ELISA
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	B cell surface antigen CD40;B cell-associated molecule;Bp50;CD40 molecule,TNF receptor superfamily member 5;CD40L receptor;CDW40;p50;TNFRSF5;tumor necrosis factor receptor superfamily member 5.
Shipping Condition	Cool pack
Available
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Manufacturer - Isotype	Rabbit IgG
Shipping Temperature	Wet Ice
Molecular Weight	35
Manufacturer - Application Additional Information	WB: 0.1-1 ug/ml \| ELISA: 0.01-0.1 ug/ml \| IP: 2-5 ug/ml \| IHC: 2-10 ug/ml \| FC: Not tested
Gene symbol	CD40
Gene Fullname	CD40 molecule
Product format	Liquid. This affinity purified antibody is supplied in sterile Phosphatebuffered saline (pH7.2) containing antibody stabilizer
Reconstitution and storage	The antibodies are stable for 24 months from date of receipt when stored at -20C to -70C. The antibodies can be stored at 2C-8C for three month without detectable loss of activity. Avoid repeated freezing-thawing cycles.
Description of target	The CD40 is a member of the TNF-receptor superfamily. It is a receptor on antigen-presenting cells of the immune system and is essential for mediating a broad variety of immune and inflammatory responses including T-cell dependent immunoglobulin class switching, memory B cell development, and germinal center formation. AT-hook transcription factor AKNA is reported to coordinately regulate the expression of this receptor and its ligand, which may be important for homotypic cell interactions. Adaptor protein TNFR2 interacts with this receptor and serves as a mediator of the signal transduction. The interaction of this receptor and its ligand is found to be necessary for amyloid-beta-induced microglial activation, and thus is thought to be an early event in Alzheimer disease pathogenesis. Mutations affecting this gene are the cause of autosomal recessive hyper-IgM immunodeficiency type 3 (HIGM3). CD40 is a B cell surface antigen.
Clonality	Polyclonal
Purification	Affinity Purified
Immunogen	A Synthetic peptide QPVTQEDGKESRISVQERQ derived from human CD40 (258-277aa) was used as an immunogen.
Manufacturer - Specificity	CD40
Concentration	100ug/200ul

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

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Delivery expected until 2/12/2026

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