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EED Antibody (OAAJ07774)

EED Antibody (OAAJ07774)

Item no.	OAAJ07774
Manufacturer	AVIVA Systems Biology
Amount	100 ul
Category	Oncology Neuroscience Neural Transcription Factors Targets for Rodent Neurosciences Antibodies By Cell Type Blastoma Carcinoma Glioma Hematology Leukemia Lymphoma Myeloma Melanoma Sarcoma Cell Biology Cell Status Myelofibrosis Mesothelioma Immunohistochemistry Western Blot Senescence Primary Antibodies By Organ Lung Cancer Heart & Blood Cancer
Type	Antibody Polyclonal
Format	Liquid
Applications	WB, IHC
Specific against	other
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Shipping Condition	Cool pack
Available
Shipping Temperature	Wet Ice
Gene symbol	EED
Product format	Liquid
Reconstitution and storage	Store at +4C. For long term storage, aliquot and store at -20C. Avoid freeze/thaw cycles.
Description of target	Polycomb group (PcG) protein. Component of the PRC2/EED-EZH2 complex, which methylates 'Lys-9' and 'Lys-27' of histone H3, leading to transcriptional repression of the affected target gene. Also recognizes 'Lys-26' trimethylated histone H1 with the effect of inhibiting PRC2 complex methyltransferase activity on nucleosomal histone H3 'Lys-27', whereas H3 'Lys-27' recognition has the opposite effect, enabling the propagation of this repressive mark. The PRC2/EED-EZH2 complex may also serve as a recruiting platform for DNA methyltransferases, thereby linking two epigenetic repression systems. Genes repressed by the PRC2/EED-EZH2 complex include HOXC8, HOXA9, MYT1 and CDKN2A.
Protein name	Polycomb protein EED
Clonality	Polyclonal
Purification	Immunogen affinity chromatography
Immunogen	A synthetic peptide of human EED

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ul

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Delivery expected until 12/11/2025

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