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PINK1 Antibody

PINK1 Antibody

Item no.	OAAN03643-100UL
Manufacturer	AVIVA Systems Biology
Amount	100 ul
Category	Neuroscience Neuroinflammation Metabolism Diabetes Neural Mitochondrial Function Protein Aggregation, Clearance & Misfolding Antibodies Cell Biology Obesity Cell Status Immunohistochemistry Western Blot Immunofluorescence Autophagy Primary Antibodies
Format	Liquid
Applications	WB, IF, IHC
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Alias	BRPK,PARK6
Shipping Condition	Cool pack
Available
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Molecular Weight	63 kDa
Manufacturer - Application Additional Information	WB 1:500 - 1:2, 000 IHC 1:50 - 1:200 IF 1:50 - 1:200
Gene symbol	PINK1
Gene Fullname	PTEN induced putative kinase 1
Product format	Liquid
Reconstitution and storage	Store at +4C. For long term storage, aliquote and store at -20C. Avoid freeze/thaw cycles.
Description of target	Protects against mitochondrial dysfunction during cellular stress by phosphorylating mitochondrial proteins. Involved in the clearance of damaged mitochondria via selective autophagy (mitophagy) by mediating activation and translocation of PARK2. Targets PARK2 to dysfunctional depolarized mitochondria through the phosphorylation of MFN2. Activates PARK2 in 2 steps: (1) by mediating phosphorylation at 'Ser-65' of PARK2 and (2) mediating phosphorylation of ubiquitin, converting PARK2 to its fully-active form.
Nucleotide accession_num	NM_032409.2
Protein accession_num	NP_115785.1
Protein name	Vacuolar protein sorting-associated protein 35
Clonality	Polyclonal
Purification	Affinity purification
Immunogen	Recombinant Protein

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ul

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Delivery expected until 1/29/2026

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