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TRAF4 Antibody - C-terminal region

TRAF4 Antibody - C-terminal region

Item no.	OABB01159
Manufacturer	AVIVA Systems Biology
Amount	100 ug/vial
Category	Oncology Neuroscience Neural Lineage Markers Neuroinflammation Metabolism Diabetes Antibodies By Cell Type Hematology Myeloma Cell Biology Obesity Cell Culture Cytokines Cell Status Necrosis Apoptosis Immunohistochemistry Western Blot ELISA Primary Antibodies Immunostaining Stem Cell Markers
Type	Antibody Polyclonal
Format	Liquid
Applications	IHC, ELISA
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	AGPT2;ANG2;angiopoietin-2;angiopoietin-2a;angiopoietin-2B;LMPHM10;Tie2-ligand.
Available
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Gene symbol	ANGPT2
Gene Fullname	angiopoietin 2
Product format	Liquid
Reconstitution and storage	-20°C or -80°C
Description of target	TRAF4(TNF Receptor-Associated Factor 4), also called CART1 or MLN62, is a protein that in humans is encoded by the TRAF3 gene. TRAF4 is a member of the TNF receptor associated factor(TRAF) family, a family of scaffold proteins. Tomasetto et al.(1995) identified genes that are overexpressed in breast cancer by differential screening of cDNAs from breast cancer-derived metastatic axillary lymph nodes. The TRAF4 cDNA, which they designated MLN62, was mapped to 17q11-q12 by radioisotopic in situ hybridization. To investigate the biologic function of TRAF4, Regnier et al.(2002) generated Traf4-deficient mice by gene disruption.
Protein name	Angiopoietin-2
Clonality	Recombinant Monoclonal
Purification	Affinity Purified
Immunogen	A synthesized peptide derived from human Angiopoietin 2
Dilution	Binds to TEK/TIE2, competing for the ANGPT1 binding site, and modulating ANGPT1 signaling. Can induce tyrosine phosphorylation of TEK/TIE2 in the absence of ANGPT1. In the absence of angiogenic inducers, such as VEGF, ANGPT2-mediated loosening of cell-matrix contacts may induce endothelial cell apoptosis with consequent vascular regression. In concert with VEGF, it may facilitate endothelial cell migration and proliferation, thus serving as a permissive angiogenic signal.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug/vial

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Delivery expected until 12/25/2025

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