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CASP14 Antibody - C-terminal region

CASP14 Antibody - C-terminal region

Item no.	OABB01259
Manufacturer	AVIVA Systems Biology
Amount	100 ug/vial
Category	Neuroscience Neural Signaling Antibodies Cell Biology Cell Status Apoptosis Immunohistochemistry Western Blot ELISA Primary Antibodies Immunostaining
Type	Antibody Polyclonal
Format	Liquid
Applications	WB, IHC, ELISA
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	CI-30;CI-30kD;complex I 30kDa subunit;complex I-30kD;MC1DN8;NADH dehydrogenase (ubiquinone) Fe-S protein 3,30kDa (NADH-coenzyme Q reductase);NADH dehydrogenase [ubiquinone] iron-sulfur protein 3,mitochondrial;NADH dehydrogenase-ubiquinone 30 kDa subunit;NADH-ubiquinone oxidoreductase 30 kDa subunit.
Available
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Gene symbol	NDUFS3
Gene Fullname	NADH:ubiquinone oxidoreductase core subunit S3
Product format	Liquid
Reconstitution and storage	-20°C or -80°C
Description of target	Caspase 14 is an enzyme that in humans is encoded by the CASP14 gene. CASP14 belongs the evolutionarily conserved caspase family. CASP14 was assigned to chromosome 19p13.1. Using Northern blot and semiquantitative RT-PCR analyses, it was showed that CASP14 was transcriptionally upregulated during maintenance of confluent cultures of human epidermal keratinocytes. The expression and processing of this caspase may be involved in keratinocyte terminal differentiation, which is important for the formation of the skin barrier. Caspase 14 seems to play a role in keratinocyte differentiation and cornification and probably regulates maturation of the epidermis by proteolytically processing filaggrin.
Protein name	NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial
Clonality	Recombinant Monoclonal
Purification	Affinity Purified
Immunogen	A synthesized peptide derived from human NDUFS3
Dilution	Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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OABB01259-datasheet.pdf

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Amount: 100 ug/vial

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Delivery expected until 12/25/2025

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