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CD163 Antibody (OABF01014-100UL)

CD163 Antibody (OABF01014-100UL)

Item no.	OABF01014
Manufacturer	AVIVA Systems Biology
Amount	100 ul
Category	Oncology Metabolism Diabetes Glucose Homeostasis Antibodies By Cell Type Carcinoma Hematology Leukemia Cell Biology Obesity Cell Culture Cytokines Cell Status Necrosis Flow Cytometry Immunohistochemistry Western Blot ELISA Immunofluorescence Immunocytochemistry Primary Antibodies Immunostaining Immunochemistry
Type	Antibody Polyclonal
Format	Liquid
Applications	WB, FC, IF, IHC, ICC, ELISA
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus), other, Dog (Canine, Canis lupus familiaris), Horse (Equine), Pig (Porcine, Sus scrofa domesticus)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	hemoglobin scavenger receptor;M130;macrophage-associated antigen;MM130;SCARI1;scavenger receptor cysteine-rich type 1 protein M130.
Shipping Condition	Cool pack
Available
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Applications	Enzyme-linked immunosorbent assay\|Flow cytometry\|Immunocytochemistry\|Immunofluorescence\|Immunohistochemistry-Frozen\|Immunohistochemistry-Paraffin\|Western blot
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Manufacturer - Application Additional Information	WB: 1:500~2000 ELISA: 1:5000~10000FC: 1:100 IHC-P: 1:100~500 IHC-F: 1:100~500Fluorescent-IHC-P: 1:100~500Fluorescent-IHC-F: 1:100~500Fluorescent-ICC: 1:100~500ICC: 1:100~500
Gene symbol	CD163
Gene Fullname	CD163 molecule
Product format	Liquid. 0.01M TBS (pH 7.4) 1% BSA, 50% glycerol and 0.09% sodium azide.
Reconstitution and storage	-20°C
Description of target	Acute phase-regulated receptor involved in clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages and may thereby protect tissues from free hemoglobin-mediated oxidative damage. May play a role in the uptake and recycling of iron, via endocytosis of hemoglobin/haptoglobin and subsequent breakdown of heme. Binds hemoglobin/haptoglobin complexes in a calcium-dependent and pH-dependent manner. Exhibits a higher affinity for complexes of hemoglobin and multimeric haptoglobin of HP1F phenotype than for complexes of hemoglobin and dimeric haptoglobin of HP1S phenotype. Induces a cascade of intracellular signals that involves tyrosine kinase-dependent calcium mobilization, inositol triphosphate production and secretion of IL6 and CSF1. Isoform 3 exhibits the higher capacity for ligand endocytosis and the more pronounced surface expression when expressed in cells.
Protein name	Scavenger receptor cysteine-rich type 1 protein M130
Clonality	Polyclonal
Purification	Protein A Purified
Immunogen	KLH conjugated synthetic peptide derived from human CD163/M130
Concentration	1 ug/ul

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ul

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Delivery expected until 12/25/2025

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