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ASAH2 Antibody

ASAH2 Antibody

Item no.	OACA02612
Manufacturer	AVIVA Systems Biology
Amount	50 ug
Category	Neuroscience Metabolism Cholesterol & Lipid Metabolism Neural Development Antibodies Immunohistochemistry Western Blot ELISA Immunofluorescence Lipid & Fatty Acid Transport Enzymes Fatty Acid Catabolism Primary Antibodies Immunostaining
Type	Antibody Polyclonal
Format	Liquid
Applications	WB, IF, IHC, ELISA
Specific against	Human (Homo sapiens), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
Purity	>95%
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	acylsphingosine deacylase 2;BCDase;HNAC1;LCDase;mitochondrial ceramidase;N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2;N-acylsphingosine amidohydrolase 2;NCDase;N-CDase;neutral ceramidase;neutral/alkaline ceramidase;non-lysosomal ceramidase.
Shipping Condition	Cool pack
Available
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Gene symbol	ASAH2
Gene Fullname	N-acylsphingosine amidohydrolase 2
Product format	Liquid
Reconstitution and storage	-20°C or -80°C
Description of target	Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid at an optimal pH of 6.5-8.5 (PubMed:10781606, PubMed:26190575). Acts as a key regulator of sphingolipid signaling metabolites by generating sphingosine at the cell surface. Acts as a repressor of apoptosis both by reducing C16-ceramide, thereby preventing ceramide-induced apoptosis, and generating sphingosine, a precursor of the antiapoptotic factor sphingosine 1-phosphate. Probably involved in the digestion of dietary sphingolipids in intestine by acting as a key enzyme for the catabolism of dietary sphingolipids and regulating the levels of bioactive sphingolipid metabolites in the intestinal tract.
Nucleotide accession_num	NM_001143974
Protein accession_num	NP_001137446
Protein name	Neutral ceramidase
Clonality	Polyclonal
Purification	Protein G Purified
Immunogen	Recombinant Human Neutral ceramidase protein (255-506AA)
Formulation	50% Glycerol, 0.01M PBS, PH 7.4

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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OACA02612-datasheet.pdf

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Amount: 50 ug

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Delivery expected until 10/30/2025

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