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PIK3R1 Antibody

PIK3R1 Antibody

Item no.	OACA03445-100UG
Manufacturer	AVIVA Systems Biology
Amount	100 ug
Category	Oncology Neuroscience Neural Lineage Markers Neuroinflammation Neural Signaling Neural Adhesion Molecules Antibodies By Cell Type Blastoma Carcinoma Glioma Hematology Leukemia Lymphoma Myeloma Melanoma Sarcoma Cell Biology Cell Status Adenocarcinoma Mesothelioma Immunohistochemistry Western Blot ELISA Autophagy Cardiovascular Research Proliferation Myocardial Infarction Primary Antibodies Astrocytoma Immunostaining Calcium Binding Protein Markers Interneuron Markers
Type	Antibody Polyclonal
Format	Liquid
Applications	IHC, ELISA
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	AGM7;GRB1;IMD36;p85;p85-ALPHA;phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha;phosphatidylinositol 3-kinase regulatory subunit alpha;phosphatidylinositol 3-kinase,regulatory subunit,polypeptide 1 (p85 alpha);phosphatidylinositol 3-kinase-associated p-85 alpha;phosphoinositide-3-kinase regulatory subunit alpha;phosphoinositide-3-kinase,regulatory subunit 1 (alpha);PI3K regulatory subunit alpha;PI3-kinase subunit p85-alpha;ptdIns-3-kinase regulatory subunit alpha.
Available
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Gene symbol	PIK3R1
Gene Fullname	phosphoinositide-3-kinase regulatory subunit 1
Product format	Liquid
Reconstitution and storage	-20°C or -80°C
Description of target	Binds to activated (phosphorylated) protein-Tyr kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane. Necessary for the insulin-stimulated increase in glucose uptake and glycogen synthesis in insulin-sensitive tissues. Plays an important role in signaling in response to FGFR1, FGFR2, FGFR3, FGFR4, KITLG/SCF, KIT, PDGFRA and PDGFRB. Likewise, plays a role in ITGB2 signaling (PubMed:17626883, PubMed:19805105, PubMed:7518429). Modulates the cellular response to ER stress by promoting nuclear translocation of XBP1 isoform 2 in a ER stress- and/or insulin-dependent manner during metabolic overloading in the liver and hence plays a role in glucose tolerance improvement (PubMed:20348923).
Nucleotide accession_num	NM_001242466
Protein accession_num	NP_001229395
Protein name	Phosphatidylinositol 3-kinase regulatory subunit alpha
Clonality	Polyclonal
Purification	Protein G Purified
Immunogen	Recombinant Human Phosphatidylinositol 3-kinase regulatory subunit alpha protein (160-376AA)

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

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Delivery expected until 11/13/2025

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