Comparison

USP30 Antibody

Item no. OACA05159
Manufacturer AVIVA Systems Biology
Amount 50 ug
Category
Type Antibody Polyclonal
Format Liquid
Applications WB, IHC, ELISA
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host Rabbit
Isotype IgG
Conjugate/Tag Unconjugated
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias deubiquitinating enzyme 30;ubiquitin carboxyl-terminal hydrolase 30;ubiquitin thioesterase 30;ubiquitin thiolesterase 30;ubiquitin-specific protease 30;ubiquitin-specific-processing protease 30;ub-specific protease 30.
Shipping Condition Cool pack
Available
Manufacturer - Type
Polyclonal Antibody
Manufacturer - Category
Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature
Wet Ice
Gene symbol
USP30
Gene Fullname
ubiquitin specific peptidase 30
Product format
Liquid
Reconstitution and storage
-20°C or -80°C
Description of target
Deubiquitinating enzyme tethered to the mitochondrial outer membrane that acts as a key inhibitor of mitophagy by counteracting the action of parkin (PRKN): hydrolyzes ubiquitin attached by parkin on target proteins, such as RHOT1/MIRO1 and TOMM20, thereby blocking parkin's ability to drive mitophagy (PubMed:18287522, PubMed:24896179, PubMed:25527291, PubMed:25621951). Preferentially cleaves 'Lys-6'- and 'Lys-11'-linked polyubiquitin chains, 2 types of linkage that participate to mitophagic signaling (PubMed:25621951). Does not cleave efficiently polyubiquitin phosphorylated at 'Ser-65' (PubMed:25527291). Acts as negative regulator of mitochondrial fusion by mediating deubiquitination of MFN1 and MFN2 (By similarity).
Nucleotide accession_num
NM_001301175
Protein accession_num
NP_001288104
Protein name
Ubiquitin carboxyl-terminal hydrolase 30
Clonality
Polyclonal
Purification
Protein G Purified
Immunogen
Recombinant Human Ubiquitin carboxyl-terminal hydrolase 30 protein (101-400AA)
Formulation
50% Glycerol, 0.01M PBS, PH 7.4

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 50 ug
Available: In stock
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