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KCTD6 Antibody

KCTD6 Antibody

Item no.	OACA05439
Manufacturer	AVIVA Systems Biology
Amount	50 ug
Category	Oncology Neuroscience Neural Lineage Markers Aging & Neurological Disorders Neural Epigenetics Antibodies By Cell Type Blastoma Carcinoma Hematology Leukemia Lymphoma Myeloma Melanoma Sarcoma Immunohistochemistry ELISA Primary Antibodies Immunostaining
Type	Antibody Polyclonal
Format	Liquid
Applications	IHC, ELISA
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
Purity	>95%
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	BTB/POZ domain-containing protein KCTD6;KCASH3;KCASH3 protein;potassium channel tetramerisation domain containing 6;potassium channel tetramerization domain-containing protein 6.
Shipping Condition	Cool pack
Available
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Gene symbol	KCTD6
Gene Fullname	potassium channel tetramerization domain containing 6
Product format	Liquid
Reconstitution and storage	-20°C or -80°C
Description of target	Probable substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex mediating the ubiquitination and subsequent proteasomal degradation of target proteins. Promotes the ubiquitination of HDAC1; the function seems to depend on KCTD11:KCTD6 oligomerization. Can function as antagonist of the Hedgehog pathway by affecting the nuclear transfer of transcription factor GLI1; the function probably occurs via HDAC1 down-regulation, keeping GLI1 acetylated and inactive. Inhibits cell growth and tumorigenicity of medulloblastoma (MDB) (PubMed:21472142). Involved in regulating protein levels of ANK1 isoform Mu17 probably implicating CUL3-dependent proteasomal degradation (PubMed:22573887).
Nucleotide accession_num	NM_001128214
Protein accession_num	NP_001121686
Protein name	BTB/POZ domain-containing protein KCTD6
Clonality	Polyclonal
Purification	Protein G Purified
Immunogen	Recombinant Human BTB/POZ domain-containing protein KCTD6 protein (1-237AA)
Formulation	50% Glycerol, 0.01M PBS, PH 7.4

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50 ug

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Delivery expected until 12/25/2025

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