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HAT1 Antibody

HAT1 Antibody

Item no.	OACA06587-100UL
Manufacturer	AVIVA Systems Biology
Amount	100 ul
Category	Antibodies Immunohistochemistry Immunoprecipitation Western Blot ELISA Immunofluorescence Primary Antibodies CHiP Immunostaining
Type	Antibody Polyclonal
Format	Liquid
Applications	WB, IHC, ELISA
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
Citations	[1]The consensus coding sequences of human breast and colorectal cancers."Sjoeblom T., Jones S., Wood L.D., Parsons D.W., Lin J., Barber T.D., Mandelker D., Leary R.J., Ptak J., Silliman N., Szabo S., Buckhaults P., Farrell C., Meeh P., Markowitz S.D., Willis J., Dawson D., Willson J.K.V. Velculescu V.E.Science 314:268-274(2006). [2]Structural basis for substrate specificity and catalysis of human histone acetyltransferase 1." Wu H., Moshkina N., Min J., Zeng H., Joshua J., Zhou M.M., Plotnikov A.N.Proc. Natl. Acad. Sci. U.S.A. 109:8925-8930(2012). [3]Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features."Bienvenut W.V., Sumpton D., Martinez A., Lilla S., Espagne C., Meinnel T., Giglione C.Mol. Cell. Proteomics 11:M111.015131-M111.015131(2012)
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Histone acetyltransferase 1;histone acetyltransferase type B catalytic subunit;KAT1.
Available
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Gene symbol	HAT1
Gene Fullname	histone acetyltransferase 1
Product format	Liquid
Reconstitution and storage	-20°C or -80°C
Description of target	Acetylates soluble but not nucleosomal histone H4 at 'Lys-5' (H4K5ac) and 'Lys-12' (H4K12ac) and, to a lesser extent, acetylates histone H2A at 'Lys-5' (H2AK5ac). Has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG. May be involved in nucleosome assembly during DNA replication and repair as part of the histone H3.1 and H3.3 complexes. May play a role in DNA repair in response to free radical damage.
Nucleotide accession_num	NM_003642
Protein accession_num	NP_003633
Protein name	Histone acetyltransferase type B catalytic subunit
Clonality	Polyclonal
Purification	Affinity Purified
Immunogen	Recombinant Human Histone acetyltransferase type B catalytic subunit protein (245-419AA)

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ul

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Delivery expected until 10/30/2025

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