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IRF4 Antibody

IRF4 Antibody

Item no.	OACA06686-100UL
Manufacturer	AVIVA Systems Biology
Amount	100 ul
Category	Oncology Neuroscience Targets for Rodent Neurosciences Antibodies By Cell Type Hematology Leukemia Lymphoma Myeloma Immunohistochemistry Western Blot ELISA Primary Antibodies By Organ Immunostaining Lymphatic System Cancer
Format	Liquid
Applications	IHC, ELISA
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
Citations	[1]Solution structure of the IRF domain of human interferon regulator factor 4."RIKEN structural genomics initiative (RSGI)Submitted (OCT-2006). [2]Initial characterization of the human central proteome."Burkard T.R., Planyavsky M., Kaupe I., Breitwieser F.P., Buerckstuemmer T., Bennett K.L., Superti-Furga G., Colinge J.BMC Syst. Biol. 5:17-17(2011). [3]Molecular cloning of IBP, a SWAP-70 homologous GEF, which is highly expressed in the immune system." Gupta S., Lee A.E., Hu C., Fanzo J.C., Goldberg I., Cattoretti G., Pernis A.B.Hum. Immunol. 64:389-401(2003).
Alias	interferon regulatory factor 4;LSIRF;lymphocyte-specific interferon regulatory factor;multiple myeloma oncogene 1;MUM1;NF-EM5;SHEP8.
Available
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Gene symbol	IRF4
Gene Fullname	interferon regulatory factor 4
Product format	Liquid
Reconstitution and storage	-20°C or -80°C
Description of target	Transcriptional activator. Binds to the interferon-stimulated response element (ISRE) of the MHC class I promoter. Binds the immunoglobulin lambda light chain enhancer, together with PU.1. Probably plays a role in ISRE-targeted signal transduction mechanisms specific to lymphoid cells. Involved in CD8(+) dendritic cell differentiation by forming a complex with the BATF-JUNB heterodimer in immune cells, leading to recognition of AICE sequence (5'-TGAnTCA/GAAA-3'), an immune-specific regulatory element, followed by cooperative binding of BATF and IRF4 and activation of genes (By similarity).
Nucleotide accession_num	NM_001195286
Protein accession_num	NP_001182215
Protein name	Interferon regulatory factor 4
Clonality	Polyclonal
Purification	Affinity Purified
Immunogen	Recombinant Human Interferon regulatory factor 4 protein (180-451AA)

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ul

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Delivery expected until 1/29/2026

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