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IFT57 Antibody

IFT57 Antibody

Item no.	OACA06888
Manufacturer	AVIVA Systems Biology
Amount	50 ul
Category	Oncology Neuroscience Molecular Targets for Neuroscience Aging & Neurological Disorders Neural Signaling Antibodies By Cell Type Carcinoma Hematology Leukemia Lymphoma Cell Biology Cell Status Apoptosis Immunohistochemistry Western Blot ELISA Primary Antibodies Immunostaining
Type	Antibody Polyclonal
Format	Liquid
Applications	WB, IHC, ELISA
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
Citations	[1]"Interactions of HIPPI, a molecular partner of Huntingtin interacting protein HIP1, with the specific motif present at the putative promoter sequence of the caspase-1, caspase-8 and caspase-10 genes." Majumder P., Choudhury A., Banerjee M., Lahiri A., Bhattacharyya N.P.FEBS J. 274:3886-3899(2007). [2]"Interaction of HIPPI with putative promoter sequence of caspase-1 in vitro and in vivo." Majumder P., Chattopadhyay B., Sukanya S., Ray T., Banerjee M., Mukhopadhyay D., Bhattacharyya N.P.Biochem. Biophys. Res. Commun. 353:80-85(2007). [3]"Homer1c interacts with Hippi and protects striatal neurons from apoptosis."Sakamoto K., Yoshida S., Ikegami K., Minakami R., Kato A., Udo H., Sugiyama H.Biochem. Biophys. Res. Commun. 352:1-5(2007).
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	dermal papilla-derived protein 8;ESRRBL1;estrogen-related receptor beta like 1;estrogen-related receptor beta-like protein 1;HIP1 protein interactor;HIP1-interacting protein;HIPPI;huntingtin interacting protein-1 interacting protein;intraflagellar transport 57 homolog;intraflagellar transport protein 57 homolog;MHS4R2;OFD18.
Shipping Condition	Cool pack
Available
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Gene symbol	IFT57
Gene Fullname	intraflagellar transport 57
Product format	Liquid
Reconstitution and storage	-20°C or -80°C
Description of target	Required for the formation of cilia. Plays an indirect role in sonic hedgehog signaling, cilia being required for all activity of the hedgehog pathway (By similarity). Has pro-apoptotic function via its interaction with HIP1, leading to recruit caspase-8 (CASP8) and trigger apoptosis. Has the ability to bind DNA sequence motif 5'-AAAGACATG-3' present in the promoter of caspase genes such as CASP1, CASP8 and CASP10, suggesting that it may act as a transcription regulator; however the relevance of such function remains unclear.
Nucleotide accession_num	NM_018010
Protein accession_num	NP_060480
Protein name	Intraflagellar transport protein 57 homolog
Clonality	Polyclonal
Purification	Affinity Purified
Immunogen	Recombinant Human Intraflagellar transport protein 57 homolog protein (170-429AA)
Formulation	PBS with, 50% glycerol, pH7.3.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50 ul

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Delivery expected until 10/30/2025

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