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CDCA8 Antibody

CDCA8 Antibody

Item no.	OACA06998
Manufacturer	AVIVA Systems Biology
Amount	50 ul
Category	Oncology Antibodies By Cell Type Blastoma Carcinoma Mesothelioma Immunohistochemistry Western Blot ELISA Primary Antibodies Immunostaining
Type	Antibody Polyclonal
Format	Liquid
Applications	IHC, ELISA
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
Citations	[1]"Phosphorylation of a borealin dimerization domain is required for proper chromosome segregation." Bourhis E., Lingel A., Phung Q., Fairbrother W.J., Cochran A.G.Biochemistry 48:6783-6793(2009). [2]"Structure of a Survivin-Borealin-INCENP core complex reveals how chromosomal passengers travel together."Jeyaprakash A.A., Klein U.R., Lindner D., Ebert J., Nigg E.A., Conti E.Cell 131:271-285(2007). [3]"System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."Rigbolt K.T., Prokhorova T.A., Akimov V., Henningsen J., Johansen P.T., Kratchmarova I., Kassem M., Mann M., Olsen J.V., Blagoev B.Sci. Signal. 4:RS3-RS3(2011).
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	BOR;borealin;cell division cycle-associated protein 8;Dasra B;dasra-B;DasraB;hDasra-B;MESRGP;pluripotent embryonic stem cell-related gene 3 protein.
Shipping Condition	Cool pack
Available
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Gene symbol	CDCA8
Gene Fullname	cell division cycle associated 8
Product format	Liquid
Reconstitution and storage	-20°C or -80°C
Description of target	Component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. Major effector of the TTK kinase in the control of attachment-error-correction and chromosome alignment.
Nucleotide accession_num	NM_001256875
Protein accession_num	NP_001243804
Protein name	Borealin
Clonality	Polyclonal
Purification	Affinity Purified
Immunogen	Recombinant Human Borealin protein (1-280AA)
Formulation	PBS with, 50% glycerol, pH7.3.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50 ul

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Delivery expected until 12/25/2025

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