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NCS1 Antibody

NCS1 Antibody

Item no.	OACA07302
Manufacturer	AVIVA Systems Biology
Amount	50 ul
Category	Neuroscience Molecular Targets for Neuroscience Neural Signaling Antibodies Immunohistochemistry Western Blot ELISA Immunofluorescence Cardiovascular Research Heart Failure Primary Antibodies Immunostaining
Type	Antibody Polyclonal
Format	Liquid
Applications	WB, IHC, ELISA
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
Citations	[1]"Immunocytochemical localization and crystal structure of human frequenin (neuronal calcium sensor 1)."Bourne Y., Dannenberg J., Pollmann V., Marchot P., Pongs O.J. Biol. Chem. 276:11949-11955(2000). [2]"Initial characterization of the human central proteome." Burkard T.R., Planyavsky M., Kaupe I., Breitwieser F.P., Buerckstuemmer T., Bennett K.L., Superti-Furga G., Colinge J.BMC Syst. Biol. 5:17-17(2010). [3]"Specificity, promiscuity and localization of ARF protein interactions with NCS-1 and phosphatidylinositol-4 kinase-III beta."Haynes L.P., Sherwood M.W., Dolman N.J., Burgoyne R.D.Traffic 8:1080-1092(2006).
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	FLUP;FREQ;frequenin homolog;frequenin-like protein;frequenin-like ubiquitous protein;neuronal calcium sensor 1.
Shipping Condition	Cool pack
Available
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Gene symbol	NCS1
Gene Fullname	neuronal calcium sensor 1
Product format	Liquid
Reconstitution and storage	-20°C or -80°C
Description of target	Neuronal calcium sensor, regulator of G protein-coupled receptor phosphorylation in a calcium dependent manner. Directly regulates GRK1 (RHOK), but not GRK2 to GRK5. Can substitute for calmodulin (By similarity). Stimulates PI4KB kinase activity (By similarity). Involved in long-term synaptic plasticity through its interaction with PICK1 (By similarity). May also play a role in neuron differentiation through inhibition of the activity of N-type voltage-gated calcium channel (By similarity).
Nucleotide accession_num	NM_001128826
Protein accession_num	NP_001122298
Protein name	Neuronal calcium sensor 1
Clonality	Polyclonal
Purification	Affinity Purified
Immunogen	Recombinant Human Neuronal calcium sensor 1 protein (1-190AA)
Formulation	PBS with, 50% glycerol, pH7.3.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50 ul

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Delivery expected until 12/25/2025

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